GS0976
(R)-2-(1-(2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methyl-6-(oxazol-2-yl)-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoicacid
CAS: 1434635-54-7
Molecular Formula: C28H31N3O8S
GS0976 - Names and Identifiers
GS0976 - Physico-chemical Properties
| Molecular Formula | C28H31N3O8S |
| Molar Mass | 569.626 |
| Density | 1.42±0.1 g/cm3(Predicted) |
| Boling Point | 779.0±70.0 °C(Predicted) |
| Solubility | DMSO: ≥ 50 mg/mL |
| pKa | 3.66±0.10(Predicted) |
| Storage Condition | -20℃ |
| Physical and Chemical Properties | Bioactive Firsocostat (GS-0976, NDI-010976, ND-630) is a reversible inhibitor of acetyl CoA carboxylase (ACC). The IC50 for hACC1 and hACC2 is 2.1 nM and 6.1 nM respectively. |
GS0976 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.756 ml | 8.778 ml | 17.555 ml |
| 5 mM | 0.351 ml | 1.756 ml | 3.511 ml |
| 10 mM | 0.176 ml | 0.878 ml | 1.756 ml |
| 5 mM | 0.035 ml | 0.176 ml | 0.351 ml |
Last Update：2024-01-02 23:10:35
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Spot supply
Product Name: ND-630 Visit Supplier Webpage Request for quotationCAS: 1434635-54-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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