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Gavinostat

Givinostat

CAS: 497833-27-9

Molecular Formula: C24H27N3O4

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Gavinostat - Names and Identifiers

Name Givinostat
Synonyms CS-2025
Givinostat
Gavinostat
Givinostat(ITF-2357)
Givinostat(free base)
[6-(diethylaminomethyl)naphthalen-2-yl]methyl N-[4-(hydroxycarbamoyl)phenyl]carbamate
[4-[(Hydroxyamino)carbonyl]phenyl]carbamic acid [6-[(diethylamino)methyl]-2-naphthalenyl]methyl ester
Carbamic acid, N-[4-[(hydroxyamino)carbonyl]phenyl]-, [6-[(diethylamino)methyl]-2-naphthalenyl]methylester
CAS 497833-27-9

Gavinostat - Physico-chemical Properties

Molecular FormulaC24H27N3O4
Molar Mass421.49
Density1.259
pKa8.97±0.10(Predicted)
Storage Condition2-8℃
UseGivinostat (ITF-2357) is an HDAC inhibitor. Inhibition of HDAC1 and HDAC3 with an IC50 of 198 nM and 157 nM, respectively.
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