Gelsevirine
Gelsevirine
CAS: 38990-03-3
Molecular Formula: C21H24N2O3
Gelsevirine - Names and Identifiers
| Name | Gelsevirine |
| Synonyms | Gelsevirine 1-Methoxygelsemine Gelsemine, 1-methoxy- Spiro[3,5,8-ethanylylidene-1H-pyrano[3,4-c]pyridine-10,3'-[3H]indol]-2'(1'H)-one,5-ethenyl-3,4,4a,5,6,7,8,8a-octahydro-1'-methoxy-7-methyl-,(3R,3'S,4aR,5S,8S,8aS,9S)- |
| CAS | 38990-03-3 |
Gelsevirine - Physico-chemical Properties
| Molecular Formula | C21H24N2O3 |
| Molar Mass | 352.43 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Melting Point | 245℃ |
| Boling Point | 130-150 °C(Press: 0.0001 Torr) |
| Specific Rotation(α) | -4.5 |
| Appearance | oily |
| pKa | 8.85±0.40(Predicted) |
| Storage Condition | 2-8℃ |
Gelsevirine - Reference
| Reference Show more | 1. Ren Li, Li gaupan, Manet, etc. Analysis on the material basis of the efficacy of reducing toxicity of Gelsemium processing [J]. Chinese Journal of Experimental prescriptions, 2020. 2. Wang Wen-yi, Tan Xing-Hui, Wang Wanying, Manet, Liao Hua-jun, Wu Shui-shui, Li Desson. Study on in vitro and in vivo content changes of Gelsemium alkaloids based on the attenuation of didangtang [J]. Chinese Journal of Information on traditional Chinese medicine, 2021,28(01):100-106. 3. [IF = 5.81] Rongcai Yue et al."Sempervirine inhibitors." Front Pharmacol. 2021 Dec 7;12:806091 |
Gelsevirine - Introduction
Gelsevirine is a common natural alkaloid, belonging to a class of pyrrole alkaloids. The following is an introduction to the nature, use, formulation and safety information of Gelsevirine:
1. Nature:
-Appearance: Gelsevirine is needle-like crystal or yellowish crystal.
-Solubility: Gelsevirine is soluble in water, alcohol and chloroform and other organic solvents, slightly soluble in ether.
-Chemical properties: Gelsevirine is an alkaline compound, slightly corrosive.
2. Use:
-Pharmaceutical field: Gelsevirine can be used in the manufacture of drugs, such as antibiotics.
-Synthesis field: Gelsevirine can be used as raw materials and intermediates in synthetic organic chemistry.
3. Preparation method:
- Gelsevirine can be extracted from natural plants and other biological sources.
-Using the method of chemical synthesis, usually using pyrrole alkaloids as raw materials, after a series of reactions and separation and purification steps, pure Gelsevirine can be obtained.
4. Safety Information:
- Gelsevirine has a certain toxicity, so safety should be paid attention to during use and handling.
-Wear appropriate protective measures such as lab coat, gloves and goggles when exposed to Gelsevirine.
-Avoid inhaling Gelsevirine dust or solution, and ensure that the operation is well ventilated.
-if accidentally contact, should immediately rinse with plenty of water, if discomfort, please seek medical attention.
1. Nature:
-Appearance: Gelsevirine is needle-like crystal or yellowish crystal.
-Solubility: Gelsevirine is soluble in water, alcohol and chloroform and other organic solvents, slightly soluble in ether.
-Chemical properties: Gelsevirine is an alkaline compound, slightly corrosive.
2. Use:
-Pharmaceutical field: Gelsevirine can be used in the manufacture of drugs, such as antibiotics.
-Synthesis field: Gelsevirine can be used as raw materials and intermediates in synthetic organic chemistry.
3. Preparation method:
- Gelsevirine can be extracted from natural plants and other biological sources.
-Using the method of chemical synthesis, usually using pyrrole alkaloids as raw materials, after a series of reactions and separation and purification steps, pure Gelsevirine can be obtained.
4. Safety Information:
- Gelsevirine has a certain toxicity, so safety should be paid attention to during use and handling.
-Wear appropriate protective measures such as lab coat, gloves and goggles when exposed to Gelsevirine.
-Avoid inhaling Gelsevirine dust or solution, and ensure that the operation is well ventilated.
-if accidentally contact, should immediately rinse with plenty of water, if discomfort, please seek medical attention.
Last Update：2024-04-09 20:49:11
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CAS: 38990-03-3
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Mobile: 18021002903
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CAS: 38990-03-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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