Glucoperiplocymarin
Periplocoside
CAS: 13137-64-9
Molecular Formula: C36H56O13
Glucoperiplocymarin - Names and Identifiers
Glucoperiplocymarin - Physico-chemical Properties
| Molecular Formula | C36H56O13 |
| Molar Mass | 696.82 |
| Density | 1.1241 (rough estimate) |
| Melting Point | 205°C |
| Boling Point | 610.7°C (rough estimate) |
| Specific Rotation(α) | D20 +32° |
| Flash Point | 272.777°C |
| Water Solubility | 7.937g/L(cold water) |
| Solubility | Soluble in methanol, DMSO |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White powder or crystal |
| pKa | 12.89±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Stability | The pH value of the simulated digestive solution is an important factor affecting the stability of periplocin. Periplocin is unstable in a simulated fasting gastric juice environment with pH=1.2 |
| Refractive Index | 1.7500 (estimate) |
| MDL | MFCD01745141 |
| Physical and Chemical Properties | Soluble in methanol, DMSO derived from Cicarp |
Glucoperiplocymarin - Risk and Safety
| Toxicity | LD in rabbits, rats (mg/kg): 10, 480 s.c. (MacKeith) |
Glucoperiplocymarin - Reference
| Reference Show more | 1. Lei Chen, Pan Jiang, Jinsong Li, Zijian Xie, Yunhui Xu, Wei Qu, Feng Feng, Wenyuan Liu, Periplocin promotes wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase, Phytomedicine, Volume 57, 2019, Pages 72-83, ISSN 094 2. Chen, Lei, et al. "Chemical profiling and the potential active constituents responsible for wound healing in Periploca forrestii Schltr." Journal of ethnopharmacology 224 (2018): 230-241.https://doi.org/10.1016/j.jep.2018.04.023 3. [IF=4.36] Lei Chen et al."Chemical profiling and the potential active constituents responsible for wound healing in Periploca forrestii Schltr."J Ethnopharmacol. 2018 Oct;224:230 4. [IF=4.18] Lei Chen et al."Periplocin promotes wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase."Phytomedicine. 2019 Apr;57:72 5. [IF=3.414] Jinsong Li et al."Effects of Periploca forrestii Schltr on wound healing by Src meditated Mek/Erk and PI3K/Akt signals."J Ethnopharmacol. 2019 Jun;237:116 6. [IF=4.452] Gangyin Xie et al."Periplocin inhibits the growth of pancreatic cancer by inducing apoptosis via AMPK-mTOR signaling."Cancer Med-Us. 2021 Jan;10(1):325-336 7. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150 |
Glucoperiplocymarin - Introduction
Periplocoside is a natural toxin that is widely found in the roots, bark, leaves and sap of the bark of the bark tree. This compound is colorless crystalline, has a bitter taste, and is soluble in water and some organic solvents.
Periplocoside has important biological activities in medical research and is widely used to treat cancer, inflammation and immune system related diseases. It has been found to have antibacterial, antiviral and antitumor activities, and is able to inhibit abnormal cell proliferation and regulate immune function.
There are many ways to make Periplocoside, mainly including extraction and purification and chemical synthesis. The extraction and purification method is to separate the Periplocoside from the Barbaris, and after physical and chemical treatment, the purified compound is finally obtained. The chemical synthesis method is to synthesize the structure of Periplocoside by organic synthesis chemical reaction.
You need to pay attention to safety information when using Periplocoside. Due to their toxicity, laboratory safety procedures must be followed and appropriate protective equipment such as gloves, glasses and protective clothing must be worn. Periplocoside has a pungent odor and should be operated in a well-ventilated area to avoid inhaling toxins. At the same time, avoid contact of the Periplocoside with the skin and eyes, and avoid accidental ingestion. If you have been exposed to or inhaled Periplocoside by accident, you should immediately seek medical attention and inform your doctor about the information.
Periplocoside has important biological activities in medical research and is widely used to treat cancer, inflammation and immune system related diseases. It has been found to have antibacterial, antiviral and antitumor activities, and is able to inhibit abnormal cell proliferation and regulate immune function.
There are many ways to make Periplocoside, mainly including extraction and purification and chemical synthesis. The extraction and purification method is to separate the Periplocoside from the Barbaris, and after physical and chemical treatment, the purified compound is finally obtained. The chemical synthesis method is to synthesize the structure of Periplocoside by organic synthesis chemical reaction.
You need to pay attention to safety information when using Periplocoside. Due to their toxicity, laboratory safety procedures must be followed and appropriate protective equipment such as gloves, glasses and protective clothing must be worn. Periplocoside has a pungent odor and should be operated in a well-ventilated area to avoid inhaling toxins. At the same time, avoid contact of the Periplocoside with the skin and eyes, and avoid accidental ingestion. If you have been exposed to or inhaled Periplocoside by accident, you should immediately seek medical attention and inform your doctor about the information.
Last Update：2024-04-09 21:11:58
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Spot supply
Product Name: Periplocin Visit Supplier Webpage Request for quotationCAS: 13137-64-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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