GlyT2-IN-1 - Names and Identifiers
GlyT2-IN-1 - Physico-chemical Properties
Molecular Formula | C13H8Cl2N4S2
|
Molar Mass | 355.27 |
Density | 1.58±0.1 g/cm3(Predicted) |
Melting Point | 136 - 138°C |
Boling Point | 538.4±60.0 °C(Predicted) |
Solubility | DMSO: ≥ 34 mg/mL |
Appearance | powder |
Color | white to beige |
pKa | -1.32±0.10(Predicted) |
Storage Condition | 2-8°C |
GlyT2-IN-1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.815 ml | 14.074 ml | 28.148 ml |
5 mM | 0.563 ml | 2.815 ml | 5.63 ml |
10 mM | 0.281 ml | 1.407 ml | 2.815 ml |
5 mM | 0.056 ml | 0.281 ml | 0.563 ml |
Last Update:2024-01-02 23:10:35
GlyT2-IN-1 - Reference Information
biological activity | Yoda1 is an agonist of human and mouse-derived Piezo1. The mouse-derived EC50 is 17.1 μM and the human-derived EC50 is 26.6 μM. In the absence of other cellular components, Yoda 1 activates purified Piezo 1 channels. |
target | TargetValue mPiezo1 (Cell-free say) 17.1 μM(EC50) hPiezo1 (Cell-free say) 26.6 μM(EC50) |
Target | Value |
mPiezo1
(Cell-free assay)
| 17.1 μM(EC50) |
hPiezo1
(Cell-free assay)
| 26.6 μM(EC50) |
Last Update:2024-04-09 21:54:55