Name | Glycitein |
Synonyms | Glycitein Glicetein GLYCITEIN GLYCETEIN Glycetein 4,7-DIHYDROXY-6-METHOXYISOFLAVONE 7,4'-DIHYDROXY-6-METHOXYISOFLAVONE 4',7-DIHYDROXY-6-METHOXYISOFLAVONE 4',7-Dihydroxy-6-methoxyisoflavone 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy- |
CAS | 40957-83-3 |
InChI | InChI=1/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3 |
InChIKey | DXYUAIFZCFRPTH-UHFFFAOYSA-N |
Molecular Formula | C16H12O5 |
Molar Mass | 284.26 |
Density | 1.420±0.06 g/cm3(Predicted) |
Melting Point | >300°C |
Boling Point | 547.4±50.0 °C(Predicted) |
Flash Point | 210°C |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Vapor Presure | 1.36E-12mmHg at 25°C |
Appearance | White powder |
Color | Light Brown |
pKa | 7.03±0.20(Predicted) |
Storage Condition | 一般在0℃~10℃之间冷藏保存(原则上保存在15℃以下的阴凉处) ,但相对于产品运输时,并不是所有产品的运输温度与储存温度一致,冷冻保 存的温度在0℃以下。 |
Refractive Index | 1.668 |
MDL | MFCD00016679 |
Physical and Chemical Properties | Derived from soybean Glycine max (L.)Merr seeds |
Hazard Symbols | Xi - Irritant |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29329990 |
Reference Show more | 1. Shen Fa Di, Zhang Zhen, Liang Wu, etc. Study on industrial-scale production of natto solid beverage containing probiotics [J]. Occupation and health, 2020, v.36(05):43-47. 2. Zhang Jing, Sun Xin. Physical and chemical properties of soybean milk fermented by Lactobacillus plantarum YS1 isolated from natural fermented yak yogurt [J]. Science and technology innovation and application, 2020, No.307(15):41-42. 3. Jin Yuhui, Liu Changzhong, Xu Xiang, etc. Effect of steam explosion on Soybean isoflavone in soybean residue [J]. The Chinese Journal of cereal and oil, 2017(10). 4. Guo Tianci, Zhao Shilei, Liu Shisheng. Study on hydrolysis of soybean isoflavones from soybean milk by β-glucosidase from bitter almond [J]. Food Research and Development, 2019(12). 5. Zhao Shi-lei, He Xu, Wang Ai-Zhu, et al. Study on improving the content of isoflavone aglycones in soybean milk by enzymatic method [J]. Food industry, 2019, 040(001):100-104. 6. Cao Dongying, Li Yan, Xu Wen, Sui Liqiang, Xu Wei. Analysis of isoflavone content in four kinds of black beans and finished fermented fermented soybean [J]. Pharmaceutical Research, 2020,39(10):581-584. 7. Zhou Wenhong, Guo Mimi, Bi Yanhong, Wang Chaoyu, Duan zhangqun. Preparation of aglycone-type soybean isoflavones by enzymatic hydrolysis [J]. China grease, 2020,45(12):100-104. 8. [IF = 7.514] Xiya Huang et al."Kinetic changes of nutrients and antioxidant capacities of germinated soybean (Glycine max L.) and mung bean (Vigna radiata L.) with germination time."Food Chem. 2014 Jan;143:268 9. [IF=7.514] Lu Xu et al."A systematic comparative study on the beneficial health components and antioxidant activities of commercially fermented soy products marketed in China."Food Chem. 2015 May;174:202 10. [IF=4.952] Guocheng Huang et al."Improvement in beta-carotene, vitamin B2, GABA, free amino acids and isoflavones in yellow and black soybeans upon germination."Lwt Food Sci Technol. 2017 Jan;75:488 11. [IF=3.645] Wenjie Wu et al."Simple, rapid, and environmentally friendly method for the separation of isoflavones using ultra-high performance supercritical fluid chromatography."J Sep Sci. 2017 Jul;40(13):2827-2837 12. [IF=7.514] Xiaoming Yu et al."Impact of processing technologies on isoflavones, phenolic acids, and antioxidant capacities of soymilk prepared from 15 soybean varieties."Food Chem. 2021 May;345:128612 13. [IF=4.769] Jing Han et al."Qualitative and quantitative evaluation of Flos Puerariae by using chemical fingerprint in combination with chemometrics method."J Pharm Anal. 2021 Sep;: 14. [IF=4.759] Wenjie Wu et al."An analytical strategy for accurate, rapid and sensitive quantitative analysis of isoflavones in traditional Chinese medicines using ultra-high performance supercritical fluid chromatography: Take Radix Puerariae as an example."J Chromato 15. [IF=4.411] Liqing Yin et al."Neuroprotective Potency of Tofu Bio-Processed Using Actinomucor elegans against Hypoxic Injury Induced by Cobalt Chloride in PC12 Cells."Molecules. 2021 Jan;26(10):2983 16. [IF=3.935] Yanchao Xing et al."An effective strategy for distinguishing the processing degree of Polygonum multiflorum based on the analysis of substance and taste by LC-MS, ICP-OES and electronic tongue."J Pharmaceut Biomed. 2021 Oct;205:114328 17. [IF=3.645] Qingyu Zhang et al."Quality control of Semen Hoveniae by high-performance liquid chromatography coupled to Fourier transform-ion cyclotron resonance mass spectrometry."J Sep Sci. 2021 Sep;44(18):3366-3375 18. [IF=2.984] Chenkai Wang et al."Comparative transcriptome analysis of roots, stems, and leaves of Pueraria lobata (Willd.) Ohwi: identification of genes involved in isoflavonoid biosynthesis."Peerj. 2021 Feb;9:e10885 19. [IF=1.797] Bihui Liu et al."Effects of Lactobacillus plantarum CQPC01‐fermented soybean milk on activated carbon‐induced constipation through its antioxidant activity in mice."Food Sci Nutr. 2019 Jun;7(6):2068-2082 20. [IF=3.645] Ziyun Wei et al.Studies on chemical constituents of Flos Puerariae-Semen Hoveniae medicine pair by HPLC and Fourier transform ion cyclotron resonance mass spectrometry.Journal Of Separation Science.2021 Nov 06 21. [IF=7.514] Chengwen Lu et al."Effect of pulsed electric field on soybean isoflavone glycosides hydrolysis by β-glucosidase: Investigation on enzyme characteristics and assisted reaction."Food Chem. 2022 Jun;378:132032 22. [IF=6.475] Pin Chen et al."The bioavailability of soy isoflavones in vitro and their effects on gut microbiota in the simulator of the human intestinal microbial ecosystem."Food Res Int. 2021 Dec;:110868 23. [IF=7.514] Xuefeng Chen et al."Quantitative analyses for several nutrients and volatile components during fermentation of soybean by Bacillus subtilis natto."Food Chem. 2021 Dec;:131725 24. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 |
basic information | density: 1.42g/cm3 boiling point: 547.4°C at 760 mmHg flash point: 210°C vapor pressure: 1.36 E-12mmHg at 25°C appearance: milky white or white powder |
source | 1. legume plant red clover Trifolium Pratense l whole grass 2. alfalfa Medicago sativa l whole grass 3.Pueraria lobata(Willd.)Ohei whole grass 4. soybean Glycine max (L.)Merr. seed 5. Nepal yellow flower tree Piptanthus nepalensis (Hook.)D.Don stem 6. Wingtooth bean Pterodon apparicioi Pedersoli wood 7. Pueraria lobata Pueraria thunbergiana Benth. flower 8. Guangdou root Sophora subprostrata Chun et T.Chen root 9. Honduran Dalbergia Dalbergia stevensonii Standl bark, heartwood |
pharmacological effects | (I) have estrogen and anti-estrogen properties. (II) has antioxidant effect. (III) can inhibit the activity of tyrosine protein kinase (PTK). (IV) can inhibit the activity of topological heterosylase Ⅱ. (V) has the effects of inducing programmed cell death, improving anti-cancer efficacy, inhibiting angiogenesis, etc. It is a potential cancer chemoprevention agent. Its anti-cancer effect and mechanism have broad application prospects. |
storage conditions | generally refrigerated between 0 ℃ and 10 ℃ (in principle, stored in a cool place below 15 ℃), but compared with the transportation of products, not all products are transported at the same transportation temperature as the storage temperature, and the cryopreservation temperature is below 0 ℃. |
References | http://www.chemsrc.com/cas/54239-37-1_671704.html http://www.best-reagent.com/goods-11457.html |
chemical properties | derived from soybean Glycine max (l.)Merr. seed |
use | used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: It has estrogen and anti-estrogen properties. It has an antioxidant effect. It can inhibit the activity of tyrosine protein kinase (PTK). It can inhibit the activity of topological heterosin II. It has the effects of inducing programmed cell death, improving anti-cancer efficacy, and inhibiting angiogenesis. It is a potential cancer chemoprevention agent. Its anti-cancer effect and mechanism have broad application prospects. |