Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline
GRGDSP
CAS: 91037-75-1
Molecular Formula: C22H37N9O10
Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline - Names and Identifiers
| Name | GRGDSP |
| Synonyms | GRGDSP glycyl-arginyl-glycyl-aspartyl-seryl-proline Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl- |
| CAS | 91037-75-1 |
Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline - Physico-chemical Properties
| Molecular Formula | C22H37N9O10 |
| Molar Mass | 587.58 |
| Physical and Chemical Properties | Bioactive GRGDSP is a synthetic linear RGD peptide and an integrin inhibitor. |
| Target | Integrin |
| In vitro study | It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization. |
