Molecular Formula | C206H338F3N63O66 |
Molar Mass | 4810.2656296 |
Appearance | powder |
Storage Condition | -20°C |
MDL | MFCD00802621 |
In vitro study | Urocortin, human is a selective agonist of CRF 2 receptor, with K i s of 0.4, 0.3, and 0.5 nM for human CRF 1 , rat CRF 2α and mouse CRF 2β receptors in cell assay, respectively. |
In vivo study | Urocortin (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such a effect also observed in mice after 1 μg of Urocortin i.c.v. administration. Urocortin has the potential of inducing anxiogenic behavior. |
WGK Germany | 3 |