H-D-BETA-PHE(4-F)-OH

H-D-BETA-PHE(4-F)-OH - Names and Identifiers

Name	(R)-3-Amino-3-(4-fluoro-phenyl)-propionic acid
Synonyms	R-4-F-PHA Albb-006640 H-D-BETA-PHE(4-F)-OH ?-R-4-Fluorophenylalanine -3-AMINO-3-(4-FLUORO-PHENYL (R)--(p-Fluorophenyl)alanine (R)-beta-4-Fluorophenylalanine (R)-3-(P-FLUOROPHENYL)-BETA-ALANINE (R)-3-amino-3-(4-fluorophenyl)propanoic acid (R)-3-Amino-3-(4-fluoro-phenyl)-propionic acid
CAS	151911-23-8
EINECS	200-258-5
InChI	InChI=1/C9H10FNO2/c10-7-3-1-6(2-4-7)8(11)5-9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m1/s1

H-D-BETA-PHE(4-F)-OH - Physico-chemical Properties

Molecular Formula	C9H10FNO2
Molar Mass	183.18
Density	1.289±0.06 g/cm3(Predicted)
Melting Point	245-247 °C(Solv: water (7732-18-5); acetone (67-64-1))
Boling Point	308.8±32.0 °C(Predicted)
Flash Point	140.6°C
Vapor Presure	0.000287mmHg at 25°C
pKa	3.66±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.554

H-D-BETA-PHE(4-F)-OH - Introduction

(R)-3-Amino-3-(4-fluoro-phenyl)-propionic acid is an organic compound with the chemical formula C9H10FNO2.

Nature:
(R)-3-Amino-3-(4-fluoro-phenyl)-propionic acid is a white crystalline solid with a special stereo configuration, wherein the linkage between the amino group and the phenyl ring is chiral. Its melting point is about 120-125 ° C. It has low solubility in water and is soluble in organic solvents such as alcohols and ethers at room temperature.

Use:
(R)-3-Amino-3-(4-fluoro-phenyl)-propionic acid has important uses in the field of medicine. It is a chiral derivative of an unnatural amino acid and is used as an intermediate in the synthesis of drugs and biologically active substances. Because of its effect on receptor selectivity and biological activity, it has a wide range of applications in drug research.

Method:
The preparation of (R)-3-Amino-3-(4-fluoro-phenyl)-propionic acid can be carried out by various methods. A common method is obtained by chiral modification of propionic acid after its synthesis. Alternatively, it can be synthesized by a reduction reaction of 3-amino -3-(4-fluorophenyl)-propenal.

Safety Information:
(R)-3-Amino-3-(4-fluoro-phenyl)-propionic acid is usually relatively safe under regular operation. However, chemical safety procedures must still be followed when using and handling this compound. Direct contact with the skin should be avoided to avoid inhalation of its dust or vapor. It is recommended to wear appropriate personal protective equipment such as gloves, glasses and laboratory coats when performing the operation. In addition, it should be stored in a dry, cool place, away from fire and combustible materials.

Last Update：2024-04-09 20:52:54