H-D-Lys(Fmoc)-OH - Names and Identifiers
H-D-Lys(Fmoc)-OH - Physico-chemical Properties
Molecular Formula | C21H24N2O4
|
Molar Mass | 368.43 |
Density | 1.245±0.06 g/cm3(Predicted) |
Boling Point | 609.9±55.0 °C(Predicted) |
pKa | 2.53±0.24(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
H-D-Lys(Fmoc)-OH - Introduction
1. Nature:
H-D-Lys(Fmoc)-OH is a white or off-white solid that is stable at room temperature. It has a protecting group Fmoc (fluorenylformyl) attached to the amino group (NH2), which can be removed by base or acid. It has different solubility in solvents, soluble in organic solvents such as dichloromethane, dimethylformamide and methanol, and poor solubility in water.
2. Use:
H-D-Lys(Fmoc)-OH is commonly used in peptide synthesis and protein research. Through the solid phase synthesis method, it can be linked with other amino acids to synthesize peptide chains or proteins with specific sequences. Due to the ease of removal of the Fmoc protecting group, it can be used as a temporary protecting group during the synthesis. In addition, it can also be used as a lead compound in drug development.
3. Preparation method:
The synthetic method of H-D-Lys(Fmoc)-OH is relatively complicated. One common method is to react Fmoc-lysine with D-lysine to form H-D-Lys(Fmoc)-OH. The synthesis process requires a series of steps, usually high-purity raw materials and patient operation.
4. Safety Information:
Under correct operation, H-D-Lys(Fmoc)-OH is relatively safe and non-toxic. However, due to its certain chemical activity, it has a stimulating effect on the skin, eyes and mucous membranes, so appropriate safety measures should be taken when using it, such as wearing protective gloves, glasses and lab coats, etc. At the same time, keep the laboratory well ventilated and avoid inhaling dust. If you accidentally touch or eat, you should seek medical help immediately.
Last Update:2024-04-09 21:11:58