H-D-Phg-OH
D(-)-alpha-Phenylglycine
CAS: 875-74-1
Molecular Formula: C8H9NO2
H-D-Phg-OH - Names and Identifiers
H-D-Phg-OH - Physico-chemical Properties
| Molecular Formula | C8H9NO2 |
| Molar Mass | 151.16 |
| Density | 1.2 g/cm3 (20℃) |
| Melting Point | 302°C (dec.)(lit.) |
| Boling Point | 273.17°C (rough estimate) |
| Specific Rotation(α) | -156 º (c=1,1N HCl) |
| Flash Point | 150°C |
| Water Solubility | 0.3g/100mL |
| Solubility | Aqueous Acid (Sparingly), Water (Slightly, Heated) |
| Vapor Presure | 0Pa at 25℃ |
| Appearance | White crystal |
| Color | White |
| Merck | 14,7291 |
| BRN | 2208676 |
| pKa | 1.94±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | -158 ° (C=1, 1mol/L |
| MDL | MFCD00008061 |
| Physical and Chemical Properties | White or off-white crystalline powder, melting point 302°C. |
| Use | For new drug manufacturing |
H-D-Phg-OH - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed R20 - Harmful by inhalation |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S44 - S28 - After contact with skin, wash immediately with plenty of soap-suds. S7 - Keep container tightly closed. S4 - Keep away from living quarters. |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29224995 |
H-D-Phg-OH - Introduction
Solubility in water: 0 · 3g/100ml, soluble in inorganic solvent and lye, actually insoluble in alcohol.
Last Update：2022-10-16 17:29:32
H-D-Phg-OH - Reference Information
| LogP | -1.76 at 20℃ |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | L-phenylglycine (cephalexin EP impurity A) is A derivative of glycine and A non-essential amino acid developed by human beings. Glycine is an inhibitory neurotransmitter in the spinal cord and is an allosteric modulator of NMDA receptors. synthesis of semi-synthetic penicillin and cephalosporin intermediates, used in the manufacture of ampicillin, piperacillin, cefalexin, etc. important raw materials for pharmaceutical synthesis of organic synthesis, is a semi-synthetic intermediate of ampicillin, ampicillin and other beta-lactam antibiotics. for new drug manufacturing |
Last Update：2024-04-09 20:52:54
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