Name | H-D-Pro-OMe . HCl |
Synonyms | H-D-PRO-OME HCL H-D-Pro-OMe.HCl H-D-Pro-OMe*HCl H-D-Pro-OMe·HCl D-PROLINE-OME HCL H-D-Pro-OMe . HCl D-Proline Methyl Ester HCl D-PROLINE METHYL ESTER HCL METHYL D-PROLINATE HYDROCHLORIDE D-proline methy ester hydrochloride D-PROLINE METHYL ESTER HYDROCHLORIDE D-Proline methyl ester hydrochloride D-PROLINE METHYL ESTER HYDROCHLORIDE SALT D-PYRROLIDINE-2-CARBOXYLIC ACID-METHYL ESTER HCL methyl (2R)-pyrrolidin-1-ium-2-carboxylate chloride |
CAS | 65365-28-8 |
EINECS | 000-000-0 |
InChI | InChI=1/C6H11NO2.ClH/c1-9-6(8)5-3-2-4-7-5;/h5,7H,2-4H2,1H3;1H/t5-;/m1./s1 |
Molecular Formula | C6H12ClNO2 |
Molar Mass | 165.62 |
Melting Point | 69-71°C |
Solubility | Methanol (Slightly), Water (Slightly, Sonicated) |
Appearance | White crystalline powder |
Color | White |
BRN | 4714125 |
Storage Condition | 2-8°C |
Sensitive | Hygroscopic |
Refractive Index | 32 ° (C=1, H2O) |
MDL | MFCD00000724 |
Hazard Symbols | Xi - Irritant |
Risk Codes | R36/38 - Irritating to eyes and skin. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S28 - After contact with skin, wash immediately with plenty of soap-suds. |
WGK Germany | 3 |
HS Code | 29339900 |
Application | D-proline methyl ester hydrochloride is an amino acid derivative and can be used as a Biochemical reagent. |
preparation | D-proline methyl ester hydrochloride was prepared as follows: ml methanol, 0.5mol D-proline were added to the reaction flask, after cooling to 10 ℃, 0.6mol(1.2eq) of thionyl chloride was added dropwise, and the temperature was raised to 70-80 ℃ after the addition, and the reaction was maintained for 2H under reflux condition, after the reaction of the raw material, D-proline methyl ester hydrochloride was obtained by post-treatment as a white solid, 0.44mol, loss on drying 0.18%, purity 98.2%, and yield 88.0%. |