H-DL-(2-THIENYL)GLY-OH

H-DL-(2-THIENYL)GLY-OH - Names and Identifiers

Name	α-(2-thienyl)glycine
Synonyms	H-DL-(2)THG-OH RARECHEM AK ML 0429 α-(2-thienyl)glycine LABOTEST-BB LT00233175 H-DL-(2-THIENYL)GLY-OH DL-2-(2-THIENYL)GLYCINE alpha-(2-thienyl)glycine alpha-(2-Thienyl)glycine 2-(Thiophen-2-yl)glycine DL-ALPHA-2-THIENYL-GLYCINE amino(thiophen-2-yl)acetic acid AMINO-THIOPHEN-2-YL-ACETIC ACID 2-AMINO-2-(2-THIENYL)ACETIC ACID Dl-alpha-aminothiophene-2-acetic acid (2S)-amino(thiophen-2-yl)ethanoic acid (2R)-amino(thiophen-2-yl)ethanoic acid
CAS	21124-40-3
EINECS	244-225-4
InChI	InChI=1/C6H7NO2S/c7-5(6(8)9)4-2-1-3-10-4/h1-3,5H,7H2,(H,8,9)/t5-/m1/s1

H-DL-(2-THIENYL)GLY-OH - Physico-chemical Properties

Molecular Formula	C6H7NO2S
Molar Mass	157.19
Density	1.418
Melting Point	208-210°C(lit.)
Boling Point	311.8±32.0 °C(Predicted)
Flash Point	142.4°C
Vapor Presure	0.000236mmHg at 25°C
BRN	126780
pKa	1.88±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.627
MDL	MFCD00005449

H-DL-(2-THIENYL)GLY-OH - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	10

H-DL-(2-THIENYL)GLY-OH - Introduction

Α-(2-thienyl)glycine is an amino acid derivative with the chemical formula C6H7NO2S. The following is a description of its nature, use, preparation and safety information:

Nature:
α-(2-thienyl)glycine is a white crystal or crystalline powder, soluble in water and alcohol solvents. It is a chiral molecule, there are two stereoisomers, α-(2-thienyl)glycine is a mixture.

Use:
α-(2-thienyl)glycine is an important intermediate in organic synthesis, which is used in the preparation of drugs, dyes and pesticides. It can also be used in the synthesis of polypeptide and protein components of drugs.

Method:
The preparation of α-(2-thienyl)glycine is generally obtained by reacting thiophen-2-ol with bromoacetic acid. The thiophen-2-ol is first reacted with sodium bisulfite to give the thiophene-2-mercapto compound. The thiophene-2-mercapto compound is then reacted with bromoacetic acid under basic conditions to give α-(2-thienyl)glycine.

Safety Information:
There is limited information on the safety of α-(2-thienyl)glycine. This compound is organic and should be handled, stored and used in accordance with standard laboratory safety practices, including wearing suitable protective gloves, glasses and protective clothing. In addition, the relevant substance safety data form should be read carefully before handling, and its contact with strong oxidants or flammable substances should be avoided. If you need to know more about its safety, please consult the relevant professional institutions or the safety guidance in the actual operation of the laboratory.

Last Update：2024-04-09 20:52:54