H-L-HIS(TRT)-OH
(2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate
CAS: 35146-32-8
Molecular Formula: C25H23N3O2
H-L-HIS(TRT)-OH - Names and Identifiers
| Name | (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate |
| Synonyms | H-HIS(TRT)-OH L-His(Trt)-OH H-His(Trt)-OH L-His(Trt)·H2O H-L-HIS(TRT)-OH 1-Trityl-L-histidine N'-Trityl-L-Histidine N-τ-Trityl-L-histidine 1-(Triphenylmethyl)-L-histidine L-Histidine, 1-(triphenylmethyl)- (2S)-2-amino-3-(1-tritylimidazol-4-yl)propanoicacid (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate |
| CAS | 35146-32-8 |
| EINECS | 609-078-6 |
| InChI | InChI=1/C25H23N3O2/c26-23(24(29)30)16-22-17-28(18-27-22)25(19-10-4-1-5-11-19,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-15,17-18,23H,16,26H2,(H,29,30)/t23-/m0/s1 |
H-L-HIS(TRT)-OH - Physico-chemical Properties
| Molecular Formula | C25H23N3O2 |
| Molar Mass | 397.47 |
| Density | 1.19±0.1 g/cm3(Predicted) |
| Melting Point | 210℃ |
| Boling Point | 584.8±50.0 °C(Predicted) |
| Flash Point | 307.5°C |
| Vapor Presure | 1.62E-14mmHg at 25°C |
| Appearance | Solid |
| pKa | 1.78±0.10(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.631 |
H-L-HIS(TRT)-OH - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
H-L-HIS(TRT)-OH - Introduction
(2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate((2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate) is an organic compound with the following properties:
1. Appearance: White or off-white crystalline solid.
2. Chemical structure: It is formed by connecting L-histidine with trityl and imidazole groups.
3. solubility: better solubility in water, can also be dissolved in organic solvents.
The (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate has the following applications:
1. For organic synthesis: As an important chiral reagent, it can be used to synthesize other organic molecules, such as biologically active compounds.
2. for drug research and development: due to its chiral structure,(2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate can be used to synthesize drug molecules with specific stereo configurations.
3. for biochemical research: due to the importance of histidine in biochemical reactions,(2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate can be used to study the activity and substrate specificity of related enzymes.
The common method for preparing (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate is through chemical synthesis. The specific steps include the selection of reactants, the control of reaction conditions and the separation and purification of products. Due to the complexity of the synthesis method, an organic chemistry laboratory is required for operation.
Regarding safety information, the toxicity and danger of (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate may have certain risks, so you should follow the laboratory's safety procedures and wear appropriate protective equipment during use. At the same time, according to the characteristics of the chemical, it should be stored in a dry, cool, well-ventilated place to avoid reaction with other substances. When handling this compound, care should be taken to prevent contact with the skin, eyes and mouth. If an accident occurs, flush immediately with plenty of water and seek medical assistance. When using this compound, pay close attention to any relevant safety information and carry out safe operation according to the actual situation.
1. Appearance: White or off-white crystalline solid.
2. Chemical structure: It is formed by connecting L-histidine with trityl and imidazole groups.
3. solubility: better solubility in water, can also be dissolved in organic solvents.
The (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate has the following applications:
1. For organic synthesis: As an important chiral reagent, it can be used to synthesize other organic molecules, such as biologically active compounds.
2. for drug research and development: due to its chiral structure,(2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate can be used to synthesize drug molecules with specific stereo configurations.
3. for biochemical research: due to the importance of histidine in biochemical reactions,(2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate can be used to study the activity and substrate specificity of related enzymes.
The common method for preparing (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate is through chemical synthesis. The specific steps include the selection of reactants, the control of reaction conditions and the separation and purification of products. Due to the complexity of the synthesis method, an organic chemistry laboratory is required for operation.
Regarding safety information, the toxicity and danger of (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate may have certain risks, so you should follow the laboratory's safety procedures and wear appropriate protective equipment during use. At the same time, according to the characteristics of the chemical, it should be stored in a dry, cool, well-ventilated place to avoid reaction with other substances. When handling this compound, care should be taken to prevent contact with the skin, eyes and mouth. If an accident occurs, flush immediately with plenty of water and seek medical assistance. When using this compound, pay close attention to any relevant safety information and carry out safe operation according to the actual situation.
Last Update：2024-04-09 21:11:58
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