H-Phe(3-F)-OH

H-Phe(3-F)-OH - Names and Identifiers

Name	L-3-fluorophenylalanine
Synonyms	H-Phe(3-F)-OH L-Phe(3-F)-OH L-3-FLUOROPHE L-3-Fluorophe H-m-Fluoro-Phe-OH RARECHEM BK PT 0025 M-FLUORO-PHENYLALANINE L-3-fluorophenylalanine L-3-FLUOROPHENYLALANINE 3-Fluoro-L-phenylalanine M-FLUORO-L-PHENYLALANINE (S)-2-AMINO-3-(3-FLUOROPHENYL)PROPIONIC ACID (2S)-2-azaniumyl-3-(3-fluorophenyl)propanoate
CAS	19883-77-3

H-Phe(3-F)-OH - Physico-chemical Properties

Molecular Formula	C9H10FNO2
Molar Mass	183.18
Density	1.293±0.06 g/cm3(Predicted)
Melting Point	240-245 °C
Boling Point	305.0±32.0 °C(Predicted)
Specific Rotation(α)	-25 º (C=1% IN H2O)
Appearance	powder to crystal
Color	White to Almost white
BRN	2725762
pKa	pK1:2.10(＋1);pK2:8.98(0) (25°C)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	-6 ° (C=2, 1mol/L HC
MDL	MFCD00066450

H-Phe(3-F)-OH - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
Hazard Note	Harmful

H-Phe(3-F)-OH - Introduction

L-3-fluorophenylalanine(3-fluoro-L-phenylalanine) is a natural amino acid derivative containing a fluorine atom. Its chemical formula is C9H10FNO2 and its molecular weight is 181.18g/mol.

Properties, L-3-fluorophenylalanine is a colorless crystalline solid with the natural amino acid structure of phenylalanine. It is soluble in water and alcohol at room temperature. In addition, it is optically active and exists as both levorotatory and dextrorotatory isomers.

In terms of application, L-3-fluorophenylalanine are mainly used in the research and preparation of bioactive molecules, drugs and advanced organic synthesis. Its fluorine atom replaces a hydrogen atom in phenylalanine, thus introducing new properties and reactivity, which is often used in the study of the "structure-activity relationship" of synthetic drug molecules, and drug design and development.

In terms of preparation, the L-3-fluorophenylalanine can be obtained by chemical synthesis. The general synthetic route is to fluorinate phenylalanine by substituting fluorine atoms for hydrogen atoms to synthesize L-3-fluorophenylalanine.

In terms of safety information, due to lack of relevant research and experimental evidence, the current understanding of the toxicity and safety of L-3-fluorophenylalanine is limited. Therefore, it is necessary to follow common laboratory and chemical safety practices when using and handling, such as wearing personal protective equipment, avoiding contact with skin and eyes, avoiding inhalation or ingestion, etc, and comply with relevant regulations. When it is first used, it should be tested on a small scale to understand its impact on humans and the environment. In case of any discomfort or accident, discontinue use immediately and seek professional medical advice.

Last Update：2024-04-10 22:30:50