H2N-PEG6-CH2CH2COOtBu

Name	H2N-PEG6-tBu
Synonyms	H2N-PEG6-tBu NH2-PEG6-Boc Amino-PEG6-COOtBu H2N-PEG6-CH2CH2COOtBu NH2-PEG6-CH2CH2COOtBu Amino-PEG7-t-butyl ester Amino-PEG6-t-butyl ester H2N-PEG6-CH2CH2-t-butylester
CAS	1286281-32-0

Molecular Formula	C19H39NO8
Molar Mass	409.51
Density	1.056±0.06 g/cm3(Predicted)
Boling Point	475.9±40.0 °C(Predicted)
pKa	8.74±0.10(Predicted)
Storage Condition	-20°C
In vitro study	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

biological activity	NH2-PEG6-Boc is a PROTAC linker, belonging to the PEG class. NH2-PEG6-Boc can be used to synthesize PROTAC molecules. NH2-PEG6-Boc is also a non-cleavable ADC linker containing 6-unit PEG, which can be used to synthesize antibody-coupled drugs (ADC).
target	PEGs Alkyl/ether Non-cleavable
in vitro research	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Last Update：2024-04-10 22:29:15

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CAS: 1286281-32-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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H2N-PEG6-CH2CH2COOtBu

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