H2N-RGD-OH

Name	arg-gly-asp
Synonyms	H2N-RGD-OH arg-gly-asp ARG-GLY-ASP L-ARG-GLY-ASP H-ARG-GLY-ASP-OH Arg-Gly-Asp acetate ARG-GLY-ASP PEPTIDE Arginyl-glycyl-asparagilin ARGINYL-GLYCYL-ASPARTIC ACID
CAS	99896-85-2
InChI	InChI=1/C12H22N6O6/c13-4-6(19)12(17,10(23)24)7(9(21)22)8(20)5(14)2-1-3-18-11(15)16/h5,7H,1-4,13-14,17H2,(H,21,22)(H,23,24)(H4,15,16,18)
InChIKey	IYMAXBFPHPZYIK-BQBZGAKWSA-N

Molecular Formula	C12H22N6O6
Molar Mass	346.34
Density	1.61±0.1 g/cm3(Predicted)
Melting Point	153-155℃ (ethyl ether )
Boling Point	597.205°C at 760 mmHg
Flash Point	314.979°C
Solubility	Soluble in 0.1N acetic acid at 20mg/ml
Vapor Presure	0mmHg at 25°C
Appearance	Powder
pKa	2.85±0.10(Predicted)
Storage Condition	-20°C
Sensitive	Easily absorbing moisture
Refractive Index	1.671
MDL	MFCD00057952
Use	Preferred sequence involving binding to cell surface proteins
In vitro study	RGD is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces. There are 24 integrins binding to ECM molecules in a RGD dependent manner: α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1.

WGK Germany

Tripeptide, from the amino acid sequence Arg-Gly-Asp of fibrocyte attachment domain

Last Update：2022-10-16 17:30:34

biological activity	RGD is a tripeptide that can effectively cause cell adhesion, localizing a specific cell line and generating a specific cellular response; Capable of binding to integrins.
Target	Integrin

Last Update：2024-04-09 20:52:54

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QQ: 3008007409

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H2N-RGD-OH

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