HEARTLEAFHOUTTUYNIAP.E.
Helicid
CAS: 80154-34-3
Molecular Formula: C13H16O7
HEARTLEAFHOUTTUYNIAP.E. - Names and Identifiers
| Name | Helicid |
| Synonyms | Helicid HELICID HELICIDE HILICIDUM HELICIDUM Gynostemma HEARTLEAFHOUTTUYNIAP.E. 4-Formylphenylb-D-allopyranoside 4-formylphenyl β-D-glucopyranoside 2-formylphenyl beta-L-glucopyranoside 4-(beta-D-allopyranosyloxy)-benzaldehyde |
| CAS | 80154-34-3 |
| EINECS | 1592732-453-0 |
| InChI | InChI=1/C13H16O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-5,9-13,15-18H,6H2/t9-,10-,11+,12-,13-/m1/s1 |
| InChIKey | OLZAGZCCJJBKNZ-VLJOUNFMSA-N |
HEARTLEAFHOUTTUYNIAP.E. - Physico-chemical Properties
| Molecular Formula | C13H16O7 |
| Molar Mass | 284.26 |
| Density | 1.510±0.06 g/cm3(Predicted) |
| Melting Point | 199-200°C |
| Boling Point | 559.9±50.0 °C(Predicted) |
| Specific Rotation(α) | -27 º (c=3.2, MeOH) |
| Flash Point | 215.7°C |
| Water Solubility | Soluble in hot water. Slightly soluble in water, ethanol or carbinol. Insoluble in aether or chloroform. |
| Solubility | Soluble in NaOH aqueous solution, slightly soluble in methanol, almost insoluble in petroleum ether, ether chloroform, dichloromethane. |
| Vapor Presure | 2.26E-13mmHg at 25°C |
| Appearance | White needle crystal (methanol) |
| Color | White to Off-white |
| pKa | 12.72±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.65 |
| MDL | MFCD00210992 |
| Physical and Chemical Properties | alpha:-27 o (c=3.2, MeOH) |
| Use | Has a strong analgesic, sedative, sleep effect |
HEARTLEAFHOUTTUYNIAP.E. - Risk and Safety
| HS Code | 29389090 |
HEARTLEAFHOUTTUYNIAP.E. - Reference Information
| Use | the bean curd element is a monomer extracted from the fruit of the wild plant shanlong Ophthalmic radish tree. White crystalline powder, sedative, used for neurasthenia, neurasthenia syndrome and angioneurotic headache. for content determination/identification/pharmacological experiments and other pharmacological effects: In clinical for neurasthenia, Sleep Initiation and Maintenance Disorders, Head Pain, Head Pain of the adjuvant therapy, 20 years of clinical application history shows: it is a safe and effective drug for the treatment of nervous system diseases. Recent studies have found that the anti-depressant activity, but the effect is general. |
| Brief description | , it is an effective component isolated from the fruit of the deep green mountain longan, and its chemical structure is similar to that of gastrodin (p-hydroxymethylbenzene-o-β-D-glucopyranoside), pharmacological and clinical studies have shown that, for the central nervous system with gastrodioside similar effects, but its sedative, sleep, analgesic effect is stronger than gastrodioside, for the treatment of neurosis curative effect is determined and no rebound Sleep Initiation and Maintenance Disorders and produce drug dependence and other side effects, has good clinical value. The products made from them, the tablets of elliferin, have been used clinically.|
| extraction and separation | FIG. 1 is a process flow chart of extraction and separation of helicid from longan fruit of deep green mountain. |
| determination of content | HPLC method (1) chromatographic conditions column: YWCT-C18(25cm × 2.6, 10 m) high pressure slurry loading method. Mobile phase: Methanol-Water (20:80); Flow rate: 0.7/min; Column temperature: room temperature; UV detection wavelength: 270nm; Paper speed: 2.5/min. (2) preparation of reference solution The reference product of helicid was precisely weighed, and 1 mg/ml solution was made with 20% methanol. Bergenin was accurately weighed, dissolved in 20% methanol, solubilized by ultrasonic wave, and prepared into an internal standard solution containing about 2 mg/mL bergenin. (3) preparation of sample solution precisely weigh about 1g of dried bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd bean curd, put it in 25ml measuring flask, add 20ml methanol to soak it for 0.5h, and extract it with ultrasonic wave for 80min, it is cooled, fixed to 25ml with methanol, filtered, and the filtrate is the sample solution. (4) determination take the solution of the reference product of the bean curd fruit glycosides in a 5ml measuring flask, add 1.5ml of bergenin internal standard solution, dilute with 20% methanol to the scale, mix well; Take 5ml of sample solution, volatilize to dryness, add 1.5ml of internal standard solution, dilute with 20% methanol to scale, and mix well. 5 μl of the reference substance and the sample solution were taken respectively, injected, measured according to the chromatographic conditions, and the content was calculated by peak area ratio. (5) determination results by using the above internal standard method, the contents of helicid in samples I and II were determined, and the results were 0.963% and 0.928%. |
| Application | its chemical structure is similar to that of Gastrodia elata, and it has strong analgesic, sedative and hypnotic effects. For neurasthenia, neurasthenia syndrome, neurosis, vascular headache, trigeminal neuralgia. Neurasthenia caused by Head Pain, dizziness, sleep disorders have obvious effect. |
Last Update：2024-04-09 21:54:55
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Product Name: Helicid Visit Supplier Webpage Request for quotationCAS: 80154-34-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Silymarin Visit Supplier Webpage Request for quotationCAS: 65666-07-1
Tel: +86-(0)731-84213302
Email: sales@staherb.cn
Mobile: +86 13875855783
QQ: 484702402
WhatsApp: +86 18374838656
Linkedin: +86 18374838656
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