HJC-0350 - Names and Identifiers
HJC-0350 - Physico-chemical Properties
Molecular Formula | C15H19NO2S
|
Molar Mass | 277.38 |
Density | 1.13±0.1 g/cm3(Predicted) |
Boling Point | 434.6±55.0 °C(Predicted) |
Solubility | DMSO: soluble5mg/mL, clear |
Appearance | powder |
Color | white to beige |
pKa | -6.94±0.70(Predicted) |
Storage Condition | room temp |
In vitro study | HJC0350 selectively blocks cAMP-induced EPAC2 activation, but does not inhibit cAMP-mediated PKA activation. In HEK293/EPAC2-FL cells, HJC0350 also inhibited 007-am-mediated activation of EPAC2 in cells. |
HJC-0350 - Risk and Safety
HJC-0350 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 3.605 ml | 18.026 ml | 36.052 ml |
5 mM | 0.721 ml | 3.605 ml | 7.21 ml |
10 mM | 0.361 ml | 1.803 ml | 3.605 ml |
5 mM | 0.072 ml | 0.361 ml | 0.721 ml |
Last Update:2024-01-02 23:10:35
HJC-0350 - Reference Information
biological activity | HJC0350 is a potent and selective inhibitor of EPAC2 with an IC50 of 0.3 μm and no inhibition of epac1. |
Target | IC50: 0.3 µm (EPAC2) |
Last Update:2024-04-09 18:58:34