Name | Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 2',4',5',7'-tetrafluoro-3-oxo-3',6'-bis[[(trifluoromethyl)sulfonyl]oxy]- |
Synonyms | HKSOX-1 Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 2',4',5',7'-tetrafluoro-3-oxo-3',6'-bis[[(trifluoromethyl)sulfonyl]oxy]- |
CAS | 1786411-17-3 |
Molecular Formula | C23H6F10O11S2 |
Molar Mass | 712.4 |
In vitro study | HKSOX-1 (10 μM) reacts with O 2 •- in potassium phosphate buffer at 25 °C to produce a dramatic time-dependent fluorescence increase, which is completed within 10 min, and the fluorescence intensity remains unchanged within 60 min. HKSOX-1 (10 μM) exhibits excellent stability toward pH changes in the range of 2.2-8.8. |
Biological activity | HKSOX-1 is a fluorescent probe used to image and detect living cells and endogenous superoxides in vivo. HKSOX-1 has excellent selectivity and sensitivity to superoxide anion radicals. |
in vitro study | HKSOX-1 (10 μ m) reacts with O 2 •- in potassium phosphate buffer at 25 c to produce a dramatic time-dependent fluorescence increase, which is completed within 10 min, and the fluorescence intensity remains unchanged within 60 min. hksox -1 (10 μ m) exhibits excellent stability toward pH changes in the range of 2.2-8.8. |