HO-PEG-NHS - Names and Identifiers
HO-PEG-NHS - Physico-chemical Properties
HO-PEG-NHS - Introduction
NHS-PEG-OH(NHS-PEG-OH) is a compound consisting of an active ester group (NHS group) and a polyethylene glycol hydroxyl group.
The presence of the NHS group makes the NHS-PEG-OH active and can be covalently coupled to other compounds. It is commonly used in drug delivery systems as crosslinking agents, stabilizers, solubilizers, PEGylation reagents and enzyme-linked reagents.
A common method of preparing NHS-PEG-OH is by reacting PEG-OH with N-hydroxysuccinimide (NHS). This reaction generates a stable ester bond and introduces an NHS group onto the polyethylene glycol chain.
Regarding safety information, NHS-PEG-OH are generally relatively safe. However, as with any chemical substance, use should be in accordance with appropriate laboratory practices and personal protective measures. In addition, safety and toxicity need to be carefully evaluated according to specific applications and uses. Therefore, before using the NHS-PEG-OH, you should carefully read the safety data sheet provided by the supplier and take safety measures according to the specific situation.
Last Update:2024-04-09 20:52:54