HOOCCH2CH2O-PEG8-CH2CH2COOH

Name	Bis-PEG10-acid
Synonyms	Bis-PEG25-acid COOH-PEG8-COOH Bis-PEG10-acid HOOC-PEG8-COOH HOOCCH2CH2-PEG24-CH2CH2COOH HOOCCH2CH2O-PEG8-CH2CH2COOH α,ω-dipropionic acid octaethylene glycol
CAS	1268488-70-5

Molecular Formula	C22H42O13
Molar Mass	514.56
Density	1.174±0.06 g/cm3(Predicted)
Boling Point	630.0±55.0 °C(Predicted)
pKa	3.97±0.10(Predicted)
Storage Condition	2-8°C
In vitro study	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

biological activity	Bis- PEG9- acid is a PROTAC linker, belonging to the PEG class. Bis- PEG9- acid can be used to synthesize a series of PROTAC molecules. Bis- PEG9- acid is a degradable (cleavable) ADC linker used in the synthesis of antibody-coupled drugs (ADCs).
target	PEGs Cleavable
in vitro study	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Last Update：2024-04-09 15:16:39

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Product Name: Bis-PEG10-acid Visit Supplier Webpage Request for quotation
CAS: 1268488-70-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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HOOCCH2CH2O-PEG8-CH2CH2COOH

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