Molecular Formula | C24H30O7 |
Molar Mass | 430.49 |
Density | 1.158 |
Melting Point | 129-130℃ |
Boling Point | 511.1±50.0 °C(Predicted) |
Appearance | Powder |
Storage Condition | 2-8℃ |
In vitro study | Hypophyllanthin down-regulates COX-2, TNF-α, and IL-1β gene expressions in U937 macrophages by interfering with the activation of NF-κB, MAPKs, and Akt. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
Reference Show more | 1. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 |
biological activity | hypophyltanthin is a major lignin in Phyllanthus spp and has strong anti-inflammatory activity. Hypophillanthin can directly inhibit P-gp of the activity without interfering with MRP2 activity. |
Target | P-gp |