Heptakis(6-amino-6-deoxy)-beta--Cyclodextrin - Names and Identifiers
Name | Heptakis(6-amino-6-deoxy)-beta--Cyclodextrin
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Synonyms | All-amino beta-cyclodextrin Heptakis(6-deoxy-6-amino)β-cd heptakis(6-deoxy-6-amino)beta-CD Heptakis(6-amino-6-deoxy)-β-cyclodextrin Heptakis(6-aMino-6-deoxy) b-cyclodextrin Heptakis(6-amino-6-deoxy)-beta-cyclodextrin Heptakis(6-amino-6-deoxy)-beta--Cyclodextrin β-Cyclodextrin,6A,6B,6C,6D,6E,6F,6G-heptaamino-6A,6B,6C,6D,6E,6F,6G-heptadeoxy
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CAS | 30754-24-6
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EINECS | 1312995-182-4 |
Heptakis(6-amino-6-deoxy)-beta--Cyclodextrin - Physico-chemical Properties
Molecular Formula | C42H77N7O28
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Molar Mass | 1128.1 |
Density | 1.520±0.06 g/cm3(Predicted) |
Melting Point | 208 °C |
Boling Point | 1453.9±60.0 °C(Predicted) |
Water Solubility | Insoluble in water, soluble in acid solution |
pKa | 11.76±0.70(Predicted) |
Storage Condition | Room Temprature |
Use | The amino beta cyclodextrin can be protonated under neutral or acidic pH conditions, and has a good complex ability with negatively charged guest molecules.
Amino group is a good bond chain group, and carboxylic acids, esters, anhydrides, aldehydes, ketones, alkyl halides can be achieved under mild conditions, amino beta cyclodextrin is a good supramolecular structure of the intermediate.
Amino beta cyclodextrin has a good catalytic effect on the specific reaction. |
Heptakis(6-amino-6-deoxy)-beta--Cyclodextrin - Introduction
Heptakis(6-amino-6-deoxy)-beta-Cyclodextrin, also known as Hep-β-CD, is a cyclodextrin derivative. It consists of seven 6-amino-6-deoxyglucose units, and the chemical structure is β-cyclic. The following is a description of the nature, use, preparation and safety information of Heptakis(6-amino-6-deoxy)-beta-Cyclodextrin:
Nature:
-Appearance: White crystalline powder
-Solubility: Slightly soluble in water, can be dissolved in organic solvents
-Thermal stability: stable at room temperature, but will decompose at high temperature
- pH stability: good stability to acid and alkali
-Environmental impact: Non-toxic to the environment and biodegradable
Use:
-Drug delivery system: Heptakis(6-amino-6-deoxy)-beta-Cyclodextrin can form inclusion complexes with non-polar drugs, improve their solubility and stability, and help drug absorption and release.
-Synthesis catalyst: Heptakis(6-amino-6-deoxy)-beta -- Cyclodextrin can be used as a catalyst carrier for the synthesis of organic compounds.
-Food industry: Heptakis(6-amino-6-deoxy)-beta -- Cyclodextrin can be used as food additives to improve the texture and freshness of food.
Preparation Method:
Heptakis(6-amino-6-deoxy)-beta-Cyclodextrin are usually obtained by free radical substitution reactions. First, β-cyclodextrin is reacted with phosphorus bromide to form 6-bromo-β-cyclodextrin. The 6-bromo-β-cyclodextrin is then reacted with ammonia to produce the Heptakis(6-amino-6-deoxy)-beta-Cyclodextrin.
Safety Information:
-Non-irritating to skin and eyes, but direct contact should be avoided
-No acute toxicity, but use should follow routine safety procedures
-Should be stored in a dry, cool place, avoid high temperature and direct sunlight
-Keep away from combustibles and oxidants and avoid contact with fire sources
Please note that although Heptakis(6-amino-6-deoxy)-beta-Cyclodextrin is considered a relatively safe compound, it should be used in strict accordance with the relevant operating guidelines and safety precautions.
Last Update:2024-04-09 21:01:54