Molecular Formula | C3F6O |
Molar Mass | 166.02 |
Density | 1,32 g/cm3 |
Melting Point | −129°C(lit.) |
Boling Point | −26°C(lit.) |
Solubility | Chloroform |
Vapor Presure | 4525 mm Hg ( 21.1 °C) |
Vapor Density | 1.65 (vs air) |
Appearance | Colorless gas, which reactsvigorously with water to form hydrates |
Storage Condition | Refrigerator |
Refractive Index | 1.247 |
Physical and Chemical Properties | Non-combustible gas. |
Hazard Symbols | T - Toxic |
Risk Codes | R60 - May impair fertility R14 - Reacts violently with water R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R34 - Causes burns R63 - Possible risk of harm to the unborn child |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S7/9 - |
UN IDs | UN 2420 2.3 |
WGK Germany | 3 |
RTECS | UC2450000 |
TSCA | T |
Hazard Note | Highly Toxic |
Hazard Class | 2.3 |
Toxicity | LD50 (mg/kg) in rats: 190 orally (trihydrate), 670 dermally (sesquihydrate); in mice: 250 i.p., 180 i.v.; in rabbits: 113 dermally (trihydrate) (Kennedy) |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Use | used in the synthesis of pharmaceuticals, pesticides and organic chemicals mainly used as organic solvents, high temperature resistant and corrosion resistant coatings and adhesives can be obtained by copolymerization with ethylene chloride. Or synthetic medicines, pesticides, polymer materials and raw materials for organic chemicals. |
production method | 1. From perfluoroisobutylene by potassium permanganate oxidation. Perfluoroisobutylene is obtained by cracking tetrafluoroethylene, and after the oxidation reaction is completed, the temperature is reduced to below 30 °c. The obtained product was separated by crude distillation and potassium salt, and about 30% perfluoroacetone hydrate could be obtained at the top of the column, and more than 95% of the product could be obtained by crude distillation. 2. The isomerization of hexafluoropropylene oxide in the presence of Sb2O5 catalyst was carried out at <200 ℃ and 0.103-14.179MPa. |
category | toxic substances |
toxicity grade | poisoning |
Acute toxicity | inhalation-rat LC50: 275 PPM/3 H; Oral-rat LD50: 191 mg/kg |
flammability hazard characteristics | non-combustible; Toxic fluoride gas generated in the fire scene; liquid contact prevents scalding |
storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Separate from oxidant and food |
fire extinguishing agent | carbon dioxide, foam, dry powder |
Occupational Standard | TLV-TWA 0.7 mg (fluorine)/m3; Tel 2.1 mg (fluorine)/M3 |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
immediate life-and health-threatening concentration | 9 ppm (61 mg/m3) |
non-combustible gas. Boiling point -27. 28 °c. Melting Point -125. 45 °c. Liquid density (23.3 °c) 1.323,(25 °c) 1.318g/mL. The critical pressure is 2.834MPA. On thermal stability, 300 deg C long-term heating, no significant decomposition. Above 550 ° C., the cracking is started, and hexafluoroethane, difluorocarbon, and the like are successively generated.
It is mainly used as an organic solvent and copolymerized with ethylene oxide to obtain high temperature resistant and corrosion resistant coatings and adhesives. Or synthetic medicines, pesticides, polymer materials and raw materials for organic chemicals.
This product has moderate toxicity, has a strong stimulating effect on the skin and eyes. TLV (threshold value) 0.1*10-6. Animal experiments showed that rats were exposed to 30 minutes of IC30 = 5.52mg/L. 3 hours of LCo exposure 1. 69mg/L, showing central nervous system inhibition, in the lungs of blood, edema and bleeding; Dog inhalation concentration of 30.6 mg/L 30 minutes of this product is in anesthesia, such as the action time of 45 minutes, one of the two dogs died under the symptoms of collapse (drop in blood pressure), bleeding and edema were seen in the lungs. This product has no carcinogenicity, but has obvious teratogenic effect.
The production equipment should be closed, the workshop should be well ventilated, and the operator should wear protective equipment. If the product touches the skin and eyes, the application of water rinse, severe cases of extended treatment. Storage and transportation with steel cylinder, usually filled to 2 ~ 5MPa, stored in a cool, dry, ventilated place