Hydroxylamine
Hydroxylamine
CAS: 7803-49-8
Molecular Formula: NH2OH
Hydroxylamine - Names and Identifiers
| Name | Hydroxylamine |
| Synonyms | FH-50 NH2OH FH-50TM Oxammonium Oxyammonia HYDROXYLAMINE Hydroxylamine hydroxylamine,freebase Hydroxylamine solution hydroxylaminefree-base |
| CAS | 7803-49-8 |
| EINECS | 232-259-2 |
| InChI | InChI=1/H3NO/c1-2/h2H,1H2 |
| InChIKey | AVXURJPOCDRRFD-UHFFFAOYSA-N |
Hydroxylamine - Physico-chemical Properties
| Molecular Formula | NH2OH |
| Molar Mass | 33.03 |
| Density | 1.078 |
| Melting Point | 7°C |
| Boling Point | >100℃ |
| Water Solubility | Miscible with water, liquid ammonia and methanol. Slightly miscible with ether, benzene, carbon disulfide and chloroform. |
| Vapor Presure | 9 mm Hg ( 40 °C) |
| Appearance | Morphological white flakes or needles |
| Merck | 13,4853 |
| pKa | pK (20°) 7.97 |
| Storage Condition | Store below +30°C. |
| Stability | Stable. Incompatible with oxidizing agents, potassium dichromate, chromium trioxide, zinc, calcium, copper, sodium, ammonia, carbonyls, phosphorus halides, pyridine, hypochlorites. |
| Refractive Index | n20/D 1.393 |
| MDL | MFCD00044522 |
| Physical and Chemical Properties | Unstable white large flake or needle-like crystals. Very easy to absorb moisture and easily soluble in water. When the concentration is 100%, 10%, 20%, 30%, 40% and 50%, the relative density of the aqueous solution is: 1.2040, 1.0192, 1.0410, 1.0637, 1.0875 and 1.1122 respectively. The product decomposes in hot water and is slightly soluble in ether, benzene, carbon disulfide and chloroform. Melting point 32.05 ℃, boiling point 70 ℃(1.33kPa). |
| Use | It is used as a reducing agent in organic synthesis. |
Hydroxylamine - Risk and Safety
| Hazard Symbols | Xn - Harmful N - Dangerous for the environment  |
| Risk Codes | R5 - Heating may cause an explosion R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R43 - May cause sensitization by skin contact R48/22 - Harmful danger of serious damage to health by prolonged exposure if swallowed. R50 - Very Toxic to aquatic organisms |
| Safety Description | S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S47 - Keep at temperature not exceeding... S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3082 |
| WGK Germany | 3 |
| RTECS | NC2975000 |
| FLUKA BRAND F CODES | 4.8 |
| TSCA | Yes |
| HS Code | 28251090 |
| Hazard Class | 8 |
| Packing Group | II |
| Toxicity | LD50 i.p. in mice: 1.83 mmol/kg (Smith, Layne) |
Hydroxylamine - Upstream Downstream Industry
Hydroxylamine - Use
| chemical properties | Unstable white large flake or needle-like crystals. Very easy to absorb moisture and easily soluble in water. When the concentration is 100%, 10%, 20%, 30%, 40% and 50%, the relative density of the aqueous solution is: 1.2040, 1.0192, 1.0410, 1.0637, 1.0875 and 1.1122 respectively. The product decomposes in hot water and is slightly soluble in ether, benzene, carbon disulfide and chloroform. Melting point 32.05 ℃, boiling point 70 ℃(1.33kPa). |
| use | Used as a reducing agent in organic synthesis. |
| use | Antip body binds to fluorophore or biotin |
| production method | Add sodium ethoxide to hydroxylamine hydrochloride ethanol solution, quickly filter out the precipitated sodium hydroxide, cool the filtrate to -18 ℃ and crystallize, filter to obtain hydroxylamine. Hydroxylamine phosphate is heated and distilled (operated at 1.73kPa) to collect the fraction at 135-137 ℃, and crude hydroxylamine can also be obtained. |
| category | corroded articles |
| toxicity classification | highly toxic |
| acute toxicity | abdominal cavity-rat LD50: 59 mg/kg; abdominal cavity-mouse LD50: 60 mg/kg |
| explosive hazard characteristics | high temperature explosion |
| flammability hazard characteristics | Thermal decomposition of toxic nitrogen oxide smoke |
| storage and transportation characteristics | The warehouse is ventilated and dry at low temperature; stored separately from combustibles |
| fire extinguishing agent | water, carbon dioxide, sand |
Last Update：2024-04-10 22:41:03
Hydroxylamine - Security information
| dangerous goods mark | Xn,N |
| hazard category code | 5-22-37/38-41-43-48/22-50-40-21/22 |
| safety instructions | 23-26-36/37/39-47-61-22-46 |
| dangerous goods transport number | UN 3082 9/PG 3 |
| WGK Germany | 3 |
| F | 4.8 |
| TSCA | Yes |
| HazardClass | 8 |
| PackingGroup | II |
| customs code | 28251090 |
| toxic substance data | 7803-49-8(Hazardous Substances Data) |
| Toxicity | LD50 I .p. in mice: 1.83 mmol/kg (Smith, Layne) |
Last Update：2024-04-10 22:29:15
Hydroxylamine - Nature
| melting point | 7°C |
| boiling point | >100 °C |
| density | 1.078 g/mL at 25 °C |
| Vapor pressure | 9mm Hg ( 40 °C) |
| refractive index | n20/D 1.393 |
| RTECS number | NC2975000 |
| storage conditions | Store below 30°C. |
| acidity coefficient (pKa) | pK (20°) 7.97 |
| morphology | white flakes or needles |
| water solubility | Miscible with water, liquid ammonia and methanol. Slightly miscible with ether, benzene, carbon disulfide and chloroform. |
| Merck | 13,4853 |
| stability | Stable. Incompatible with oxidizing agents, potassium dichromate, chromium trioxide, zinc, calcium, copper, sodium, ammonia, carbonyls, phosphorus halides, pyridine, hypochlorites. |
| InChIKey | AVXURJPOCDRRFD-UHFFFAOYSA-N |
| NIST chemical information | Hydroxylamine(7803-49-8) |
| EPA chemical information | Hydroxylamine (7803-49-8) |
Last Update：2024-04-09 20:52:54
Supplier List
Spot supply
Product Name: Hydroxylamine Request for quotationCAS: 7803-49-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Hydroxylamine Request for quotationCAS: 7803-49-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: Hydroxylamine Request for quotation
CAS: 7803-49-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 7803-49-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Hydroxylamine Request for quotationCAS: 7803-49-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Hydroxylamine Request for quotationCAS: 7803-49-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: Hydroxylamine Request for quotation
CAS: 7803-49-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 7803-49-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
View History
Raw Materials for Hydroxylamine
Downstream Products for Hydroxylamine
3-Amino-3-(2-nitrophenyl)propanoic acid
(NE)-N-pentan-2-ylidenehydroxylamine
Dimethyl Oxazole
FORMAMIDOXIME
Bufexamac
(NE)-N-pentan-2-ylidenehydroxylamine
Dimethyl Oxazole
FORMAMIDOXIME
Bufexamac