INF4E
Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate
CAS: 88039-46-7
Molecular Formula: C12H13ClO3
INF4E - Names and Identifiers
INF4E - Physico-chemical Properties
| Molecular Formula | C12H13ClO3 |
| Molar Mass | 240.68282 |
| Storage Condition | -20℃ |
| Use | NLRP3-IN-9 is an inhibitor of caspase-1 and NLRP3 ATPase activities. It acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner. |
INF4E - Reference
| Reference Show more | 1: Cocco M, Garella D, Di Stilo A, Borretto E, Stevanato L, Giorgis M, Marini E, Fantozzi R, Miglio G, Bertinaria M. Electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis. J Med Chem. 2014 Dec 26;57(24):10366-82. doi: 10.1021/jm501072b. Epub 2014 Dec 4. PubMed PMID: 25418070. |
INF4E - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.155 ml | 20.774 ml | 41.549 ml |
| 5 mM | 0.831 ml | 4.155 ml | 8.31 ml |
| 10 mM | 0.415 ml | 2.077 ml | 4.155 ml |
| 5 mM | 0.083 ml | 0.415 ml | 0.831 ml |
Last Update：2024-01-02 23:10:35
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Product Name: Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate Visit Supplier Webpage Request for quotation
CAS: 88039-46-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 88039-46-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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