IRAK4-IN-4
1-(7-Methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-phenylethane-1,2-dione
CAS: 1850276-58-2
Molecular Formula: C22H16N2O2
IRAK4-IN-4 - Names and Identifiers
IRAK4-IN-4 - Physico-chemical Properties
| Molecular Formula | C22H16N2O2 |
| Molar Mass | 340.37 |
| Density | 1.20±0.1 g/cm3(Predicted) |
| pKa | 3.01±0.50(Predicted) |
| Storage Condition | 2-8°C |
IRAK4-IN-4 - Reference Information
| biological activity | IRAK4-IN-4 (compound 15) is a interleukin-1 receptor-associated kinase 4 (IRAK4) and cyclic GMP-AMP synthase (cGAS) inhibitors, corresponding to IC50 values of 2.8 nM and 2.1 nM, respectively. |
| Target | Value |
| cGAS (Cell-free assay) | 2.1 nM |
| IRAK4 (Cell-free assay) | 2.8 nM |
Last Update：2024-04-09 20:52:54
