ISF-2001
Tritiozine
CAS: 35619-65-9
Molecular Formula: C14H19NO4S
ISF-2001 - Names and Identifiers
ISF-2001 - Physico-chemical Properties
| Molecular Formula | C14H19NO4S |
| Molar Mass | 297.37 |
| Density | 1.2461 (rough estimate) |
| Melting Point | 141-143° |
| Refractive Index | 1.7500 (estimate) |
ISF-2001 - Risk and Safety
| Toxicity | LD50 i.p. in mice: 2000 mg/kg (Pifferi, 1973) |
ISF-2001 - References
| Overview | sulmemorpholine is mainly used for the treatment of gastric and duodenal ulcer and hyperacidity and other symptoms. |
| basic physical properties | Chinese name: sulmemorpholine alias: trimethylthiophenazine, ulcer Yukang, kuixiaojing, trithiazine, trithiazine English name: Tritiozine English alias: EINECS 252-645-4, Tresanil CAS number: 35619-65-9 Molecular formula: c14H19NO4S Molecular Weight: 297.37 PSA:72.25 LogP:1.658 Melting Point: 140-141 ℃ density: 1.211g/cm3 Boiling Point: 420.8°C at 760mmHg flash point: 208.3°C refractive index: 1.57 solubility: slightly soluble in water, easily soluble in chloroform appearance: light yellow crystal or crystalline powder Properties: odorless, bitter Main Ingredients: Agar, carrageenan and Agar-carrageenan polysaccharide |
| production method | at present, the preparation process of the drug is not disclosed in China. The US patent shows: trimethoxyline may be used for the preparation of sulmesomorpholine. The main synthesis path is shown below: |
| dosage | 300mg, 3 times a day. 4 weeks for a course of treatment. |
| indications | for gastric ulcer, duodenal ulcer, gastritis, duodenitis, diffuse gastric mucosal erosion, etc. |
| contraindication | is contraindicated in pregnant women and patients with hepatic dysfunction. |
| adverse reactions | a minority of patients had drowsiness, Fatigue, dry mouth, Head Pain, dizziness, numbness of fingers and toes, proteinuria, adverse reactions such as elevated serum transaminase can be recovered after stopping the drug. If the reaction is serious and cannot be tolerated (such as when the fingers and toes are tingling) or if there is an allergy, the drug should be discontinued immediately. |
Last Update：2024-04-10 22:29:15
