Indolyl-3-(ethyl--bromide) - Names and Identifiers
Indolyl-3-(ethyl--bromide) - Physico-chemical Properties
Molecular Formula | C10H10BrN
|
Molar Mass | 224.1 |
Density | 1.515±0.06 g/cm3(Predicted) |
Melting Point | 97-99 °C (lit.) |
Boling Point | 343.5±17.0 °C(Predicted) |
Solubility | chloroform: soluble25mg/mL, clear, yellow |
Appearance | Liquid |
Color | Orange-red to red |
pKa | 16.96±0.30(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Indolyl-3-(ethyl--bromide) - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
|
WGK Germany | 3 |
HS Code | 29339980 |
Hazard Class | IRRITANT |
Indolyl-3-(ethyl--bromide) - Introduction
3-(2-bromoethyl)indole is an organic compound with the chemical formula C11H10BrN. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-(2-bromoethyl)indole is a light yellow to yellow-brown crystal or solid.
-Melting point: about 50-52°C.
-Boiling point: about 300-310°C.
-Solubility: Soluble in organic solvents, such as chloroform, dimethyl sulfoxide and ether.
Use:
- 3-(2-bromoethyl)indole is commonly used as an intermediate or reagent in organic synthesis.
-It can be used to synthesize biologically active compounds, such as drugs and dyes.
Preparation Method:
The preparation of -3-(2-bromoethyl)indole can be carried out by the following steps:
1.3-indolecarboxaldehyde reacts with bromoethane under alkaline conditions to generate 3-(2-bromoethyl)indole alcohol.
2. Then, 3-(2-bromoethyl)indole alcohol is reacted with anhydrous acetic acid or substrate to generate 3-(2-bromoethyl)indole.
Safety Information:
- 3-(2-bromoethyl)indole is an organic compound and should follow the safety procedures of chemical laboratories when used.
-It may be irritating to the skin, eyes and respiratory system, and has certain toxicity.
-During use and operation, avoid inhaling gas, solution or dust, and avoid contact with skin, eyes and clothing.
-In case of accidental use or contact, seek medical attention immediately.
Last Update:2024-04-09 02:00:45