Molecular Formula | C19H16ClNO4 |
Molar Mass | 357.78764 |
Melting Point | 151-153°C |
Storage Condition | Refrigerator |
biological activity | Indomethacin-D4 (Indometacin-D4) is a deuterated compound of Indomethacin. Indomethacin is a potent, blood-brain barrier-permeable, non-selective inhibitor of COX1 and COX2 in CHO cells, the IC50 values for human COX-1 and COX-2 were 18 nM and 26 nM, respectively. Indomethacin disrupts autophagic flux by interfering with the normal function of lysosomes. |