Molecular Formula | C20H22O6 |
Molar Mass | 358.39 |
Density | 1.269±0.06 g/cm3(Predicted) |
Melting Point | 88 °C |
Boling Point | 561.9±50.0 °C(Predicted) |
Specific Rotation(α) | +125 (EtOH) |
Solubility | Insuluble (5.4E-3 g/L) (25 °C) |
Appearance | Powder |
pKa | 7.05±0.20(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD00144512 |
Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents. |
Reference Show more | 1. Enke, Zheng, Yi, ya, Liu, Jie: Li, Nong, Zheng, Jian, MA, Shuangcheng. Determination of eight hydroxynaphthoquinones in different parts of arnebia euchroma by HPLC [J]. Chinese Journal of Traditional Chinese Medicine, 2017, 42(13):2532-2537. 2. Li, Jing, Li, Yao, Lei, Yu, Jian, et al. Study on quality control of arnebia euchroma by one-Test multi-evaluation method combined with characteristic chromatogram [J]. Journal of Pharmaceutical Analysis 2020(7):1209-1216. 3. Zhong Yu, Zheng Xuebao, Cai kangrong, Huang Qionglin, Ye Hua, Huang Zhen, Wang Yongsheng, Zhu Yuzhen. Isobutyrylshikonin inhibits the proliferation of colon cancer cells via PI3K/Akt/m-TOR pathway [J]. Chinese Journal of Traditional Chinese Medicine, 2018,43(11):2358-2364. 4. Wang Ruishan, Zhou Li, Wang Sheng. Study on the establishment and effect of two CYP450 gene interference hairy root system in Xinjiang [J]. Chinese Journal of Traditional Chinese Medicine, Volume 45, 202014, pages 3422-3431, MEDLINE ISTIC PKU CSCD CA BP, 2020. 5. Dong Na, Gao Zhao Jun, Qu Xiaolan, et al. Simultaneous determination of five naphthoquinones in arnebia euchroma by HPLC [J]. Journal of Taishan Medical College, 2019, 40(05):336-338. 6. Gao Zhao-jun, Liu qiue, Qu Xiaolan, etc. Comparative study on HPLC fingerprints of arnebia euchroma and arnebia euchroma in Taishan [J]. China Modern Applied Pharmacy, 2019, 036(010):1193-1196. 7. [IF = 1.312] Qi Zhang et al."Rapid and sensitive determination of shikonin and its derivatives in the roots of Arnebia euchroma (Royle) Johnst using matrix solid-phase dispersion extraction and ultrahigh-performance liquid chromatography with photodiode array detecto |
biological activity | Isobutylshikonin is shikonin pigment derived from hairy root culture of Lithospermum canescens. |
chemical properties | soluble in methanol, ethanol, DMSO and other organic solvents. |
use | isobutyryl shikonin has anti-tumor, antibacterial, anti-inflammatory and analgesic effects. |