Isoindoline
Isoindoline
CAS: 496-12-8
Molecular Formula: C8H9N
Isoindoline - Names and Identifiers
| Name | Isoindoline |
| Synonyms | ISOINDOLINE Isoindoline Isoinodoline o-Xyleneimine DIHYDROISOINDOLE 2,3-dihydro-1H-isoindole 1,3-Dihydro-2H-isoindole 1H-Isoindole, 2,3-dihydro- 4-aMino-6-broMo-5-fluoropyriMidine |
| CAS | 496-12-8 |
| InChI | InChI=1/C8H9N/c1-2-4-8-6-9-5-7(8)3-1/h1-4,9H,5-6H2 |
| InChIKey | GWVMLCQWXVFZCN-UHFFFAOYSA-N |
Isoindoline - Physico-chemical Properties
| Molecular Formula | C8H9N |
| Molar Mass | 119.16 |
| Density | 1.05 g/mL at 25 °C (lit.) |
| Melting Point | 17 °C (lit.) |
| Boling Point | 221 °C (lit.) |
| Flash Point | 202°F |
| Vapor Presure | 0.338mmHg at 25°C |
| Appearance | Crystalline Powder, Crystals or Flakes, Darkening On Exposure To Light |
| Color | White to off-white |
| pKa | 9.26±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.57(lit.) |
Isoindoline - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29339980 |
Isoindoline - Introduction
Isoindoline, also known as Isoindoline, is a nitrogen-containing organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
- Isoindoline is a white to gray solid with a special smell.
-Its molecular formula is C8H7N and its molecular weight is 117.15g/mol.
- Isoindoline has a lower melting point and boiling point.
-The compound is almost insoluble in water, but soluble in organic solvents such as ethanol and ether.
Use:
- Isoindoline is an important intermediate in organic synthesis and can be used to synthesize a variety of organic compounds.
-It can be used to prepare dyes, pesticides, medicines and photosensitive materials.
- Isoindoline has a variety of chemical reactions, such as catalytic hydrogenation, amination and esterification.
Preparation Method:
Isoindoline can be prepared by the following methods:
-Esterification of indole with malonic anhydride.
-The condensation and dehydration reaction of indole and anhydride.
-Hydrogenation of indole to form Isoindoline by catalytic hydrogenation reaction.
Safety Information:
- Isoindoline dust may cause irritation to the skin, eyes and respiratory system.
-During use, personal protective equipment such as gloves and glasses should be used.
-Avoid inhaling Isoindoline dust and operate in a well-ventilated environment.
-The Isoindoline should be kept away from open flames and heat sources, and avoid contact with oxidants to avoid fire or explosion.
-After storage and disposal, waste should be properly disposed of and disposed of in accordance with local regulations.
Please note that this information is for informational purposes only and always follow laboratory and safe practices when using and handling chemicals.
Nature:
- Isoindoline is a white to gray solid with a special smell.
-Its molecular formula is C8H7N and its molecular weight is 117.15g/mol.
- Isoindoline has a lower melting point and boiling point.
-The compound is almost insoluble in water, but soluble in organic solvents such as ethanol and ether.
Use:
- Isoindoline is an important intermediate in organic synthesis and can be used to synthesize a variety of organic compounds.
-It can be used to prepare dyes, pesticides, medicines and photosensitive materials.
- Isoindoline has a variety of chemical reactions, such as catalytic hydrogenation, amination and esterification.
Preparation Method:
Isoindoline can be prepared by the following methods:
-Esterification of indole with malonic anhydride.
-The condensation and dehydration reaction of indole and anhydride.
-Hydrogenation of indole to form Isoindoline by catalytic hydrogenation reaction.
Safety Information:
- Isoindoline dust may cause irritation to the skin, eyes and respiratory system.
-During use, personal protective equipment such as gloves and glasses should be used.
-Avoid inhaling Isoindoline dust and operate in a well-ventilated environment.
-The Isoindoline should be kept away from open flames and heat sources, and avoid contact with oxidants to avoid fire or explosion.
-After storage and disposal, waste should be properly disposed of and disposed of in accordance with local regulations.
Please note that this information is for informational purposes only and always follow laboratory and safe practices when using and handling chemicals.
Last Update：2024-04-09 15:17:58
