KML-16

KML-16 - Names and Identifiers

Name	4-Chloro-2-(methylsulfonyl)pyrimidine
Synonyms	CMSP KML-16 4-Chloro-2-(methylsulfonyl) 4-CHLORO-2-METHANESULFONYL-PYRIMIDINE 4-Chloro-2-(methylsulfonyl)pyrimidine PyriMidine, 4-chloro-2-(Methylsulfonyl)- Pyrimidine, 4-chloro-2-(methylsulfonyl)-
CAS	97229-11-3
EINECS	1312995-182-4
InChI	InChI=1/C5H5ClN2O2S/c1-11(9,10)5-7-3-2-4(6)8-5/h2-3H,1H3

KML-16 - Physico-chemical Properties

Molecular Formula	C5H5ClN2O2S
Molar Mass	192.62
Density	1.486
Melting Point	87-89 °C
Boling Point	371.2±34.0 °C(Predicted)
Flash Point	178.3°C
Vapor Presure	2.24E-05mmHg at 25°C
pKa	-4.77±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.539

KML-16 - Risk and Safety

Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	36/37 - Wear suitable protective clothing and gloves.
HS Code	29335990

KML-16 - Introduction

4-Chloro-2-(methylsulfonyl)pyrimidine is an organic compound with the chemical formula C5H3ClN2O2S. Its nature is as follows:

Appearance: White crystalline solid
Melting point: 108-110°C
Boiling point: No data
Solubility: Soluble in some organic solvents, such as chloroform, dichloromethane and ether, slightly soluble in water

4-Chloro-2-(methylsulfonyl)pyrimidine has a variety of applications, including:

1. pesticide synthesis: as an intermediate of synthetic pesticides, used in the manufacture of pesticides, fungicides, etc.
2. pharmaceutical synthesis: can be used as a raw material for the synthesis of drugs, such as antibiotics, anti-tumor drugs.
3. Other applications: catalysts for organic synthesis reactions, metal chelating agents, etc.

4-Chloro-2-(methylsulfonyl)pyrimidine is mainly prepared by the following methods:

1. by 4-chlorine -2-hydroxyl pyrimidine and methanesulfonyl chloride reaction.
2. by 4-chloro -2-cyanopyrimidine reaction with methanesulfonic acid.

It should be noted that the safety information for the 4-Chloro-2-(methylsulfonyl)pyrimidine is as follows:

1. toxicity: 4-Chloro-2-(methylsulfonyl)pyrimidine may produce certain toxicity to human body, contact should avoid direct contact with skin and eyes. Good laboratory practices and personal protective measures should be taken, such as wearing gloves, goggles and protective clothing.
2. Fire hazard: 4-Chloro-2-(methylsulfonyl)pyrimidine can burn under high temperature and open flame.
3. Environmental Hazards: 4-Chloro-2-(methylsulfonyl)pyrimidine may have toxic effects on aquatic organisms and prevent them from entering water or soil.

In actual use, safety operation specifications should be followed and good ventilation conditions should be maintained. If any related problems or unexpected situations occur, you should immediately seek professional help and guidance.

Last Update：2024-04-09 21:21:28