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L-半胱氨酸,盐酸盐

L-Cysteine hydrochloride anhydrous

CAS: 52-89-1

Molecular Formula: C3H8ClNO2S

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L-半胱氨酸,盐酸盐 - Names and Identifiers

Name L-Cysteine hydrochloride anhydrous
Synonyms L-β-mercapto
H-Cys-OH.HCl
L-Cysteine HCl
L-Cysteine hydrochlo
L-Cysteine Hcl Anhydrous
L-Cysteine hydrochloride
L-Cysteine HCl anhydrate
Di-isopropyl nahpthalene
L-Cisteine·hydrochloride
L-Cysteine·hydrochloric acid
L-Cysteine hydrochloride anhydrous
L-(+)-α-amino-β-thiopropionic acid
L-cysteine hcl cell culture tested
L-Cysteine hydrochloride anhydrous, extra pure
2-(2-Methoxy Ethoxy) Acetaldehyde Dimethyl Actal
(2R)-2-Amino-3-sulfanylpropanoic acid hydrochloride
(2R)-2-Amino-3-mercaptopropanoic acid·hydrochloric acid
CAS 52-89-1
EINECS 200-157-7
InChI InChI=1/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/p-1
InChIKey IFQSXNOEEPCSLW-DKWTVANSSA-N

L-半胱氨酸,盐酸盐 - Physico-chemical Properties

Molecular FormulaC3H8ClNO2S
Molar Mass157.62
Melting Point180°C
Boling Point305.8°C at 760 mmHg
Specific Rotation(α)5.5 º (c=8, 6 N HCL)
Flash Point138.7°C
Water SolubilitySOLUBLE
Solubility H2O: 1M at20°C, clear, colorless
Vapor Presure0.000183mmHg at 25°C
AppearanceWhite Crystals
ColorWhite to light brown
Merck14,2781
BRN3560277
Storage ConditionInert atmosphere,Room Temperature
StabilityStable, but light, moisture and air sensitive. Incompatible with strong oxidizing agents, some metals.
SensitiveHygroscopic
MDLMFCD00064553
Physical and Chemical PropertiesWhite Crystal or crystalline powder, odor, acid, soluble in water, ammonia, acetic acid, ethanol-soluble, acetone, ethyl acetate, benzene, carbon disulfide, carbon tetrachloride. Acid stability, and in neutral or slightly alkaline solution is easy to be air oxidation into cystine, trace iron and heavy metal ions can promote oxidation. Its hydrochloride is more stable, so it is generally made into hydrochloride. L-cysteine is a sulfur-containing non-essential amino acid. In the living body, the hydroxyl oxygen atom of serine is replaced by the sulfur atom of methionine and synthesized via the thioether. L-cysteine can generate glutathione, involved in the reduction process of cells and phospholipid metabolism in the liver, can protect liver cells from damage, and can stimulate hematopoietic function, increase white blood cells, promotes the repair of skin lesions. Its mp is 175 ℃, decomposition temperature is 175 ℃, isoelectric point is 5.07, [α]25D-16.5 (H2O), [α]25D 6.5 (5mol/L, HCl).
UseWidely used in cosmetics, medicine, food and other industries

L-半胱氨酸,盐酸盐 - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany2
RTECSHA2275000
FLUKA BRAND F CODES3-10-23
TSCAYes
HS Code29309013
ToxicityLD50 intraperitoneal in mouse: 1250mg/kg

L-半胱氨酸,盐酸盐 - Nature

Open Data Verified Data

white crystals. Hygroscopic. 175~178 degrees C decomposition. Slow oxidation and decomposition in air. Soluble in water, ethanol and acetone. The aqueous solution was acidic.

Last Update：2024-01-02 23:10:35

L-半胱氨酸,盐酸盐 - Preparation Method

Open Data Verified Data

Cystine was dissolved in dilute hydrochloric acid, and the tin particles were added by filtration to warm reflux. Dilute the reducing solution with water, remove the remaining tin particles, saturate with hydrogen sulfide, filter, wash the residue with a small amount of water, combine the washing solution and filtrate, concentrate under reduced pressure, cool and crystallize, drying gave L-cysteine hydrochloride.

Last Update：2022-01-01 09:27:42

L-半胱氨酸,盐酸盐 - Introduction

Strong acid taste, odorless, only trace sulfite smell. It is an amino acid used by various tissue cells to defend against harmful substances and increase vitality in animals and plants. It is also one of more than 20 amino acids that make up proteins, and it is the only amino acid with active sulfhydryl (-SH).
Last Update：2022-10-16 17:25:48

L-半胱氨酸,盐酸盐 - Use

Open Data Verified Data

for biochemical studies. Determination of calcium and magnesium in iron and steel raw materials. The reducing agent of hemolysin was determined. For the treatment of acrylonitrile and aromatic poisoning, prevention of radiation injury, treatment of bronchitis and phlegm. Also used in cosmetics, to prevent aging, as a food additive, promote fermentation, maintain the flavor.

Last Update：2022-01-01 09:27:43

L-半胱氨酸,盐酸盐 - Reference Information

NIST chemical information Information provided by: webbook.nist.gov (external link)
EPA chemical information Information provided by: ofmpub.epa.gov (external link)
properties l cysteine hydrochloride is colorless to white crystal or crystalline powder, with slight special smell and sour taste, melting point 175 ℃ (decomposition). Soluble in water, the aqueous solution is acidic, the pH value of 1% solution is about 1.7, and the pH value of 0.1% solution is about 2.4. It can also be soluble in alcohol, ammonia and acetic acid, but insoluble in ether, acetone, benzene, etc. It has the characteristics of reducing, anti-oxidation and preventing non-enzymatic browning.
preparation method hydrolyze hair with hydrochloric acid, distill under reduced pressure, distill hydrochloric acid, then decolorize, filter, take filtrate and add ammonia to neutralize L-cystine crude crystal, then dissolve and neutralize it with ammonia water, recrystallize, then dissolve it with hydrochloric acid and electrolytically reduce, concentrate, cool, crystallize and dry.
use is used to treat radioactive drug poisoning, heavy metal poisoning, toxic hepatitis, serum sickness, etc., and can prevent liver necrosis. Used as a component of cosmetics perm, sunscreen, hair growth perfume, hair nourishing essence; can be used as a food additive to prevent vitamin C oxidation and discoloration; used in bread to promote gluten protein formation and fermentation, mold, etc.
Widely used in cosmetics, medicine, food and other industries
used in medicine, food and other
used in biochemical research, used as a reducing agent for the determination of hemolysin, used as an antidote in medicine.
Pharmaceuticals, food.
It is used to treat radioactive drug poisoning, heavy metal poisoning, toxic hepatitis, serum sickness, etc., and can prevent liver necrosis. Used as a component of cosmetics perm, sunscreen, hair growth perfume, hair nourishing essence; can be used as a food additive to prevent vitamin C oxidation and discoloration; used in bread to promote gluten protein formation and fermentation, mold, etc.
NMDA glutamatergic receptor agonists are also AMPA glutamatergic receptor agonists at high concentrations.
production method L-cystine is used as raw material, reduced with stannous chloride in hydrochloric acid medium, and then crystallized and refined.
method 1. hydrolysis-electrolysis method uses pig hair and hair as raw materials to separate cystine from cystine by hydrolysis and adjusting the isoelectric point of cystine, and then electrolytically reduce cystine to obtain cysteine. Hydrolysis separates cystine pig hair and hair [HCl, 117 ℃, 7h]→ [acid hydrolysis] hydrolysate [NaOH, pH4.8]→ [neutralization] L-cystine (crude) electrolytic reduction in two separate pools, one pool is filled with 1mol/L HCl inserted into an ink rod, connected to the positive electrode of the power supply, this pool is the anode, and the other pool is filled with cystine hydrochloric acid solution (cystine: concentrated HCl: water = 1:1:4), insert the lead plate, connect the negative pole of the power supply, this pool is the cathode. Add salt bridge connection between the two pools. Turn on the power supply to adjust the current 5A and carry out electrolysis. Electrolysis is completed for about 6-7h. Take the electrolyte and add pyridine a little drop, no turbidity indicates that the electrolysis is completed. L-cystine [HCl]→ [electrolytic reduction] L-cysteine hydrochloride [decolorization, concentration, crystallization] → L-cysteine hydrochloride crystallization decolorization, concentration, crystallization electrolysis is completed, cut off the power supply, add 10g/L(1%) activated carbon according to the feeding amount, heat to 70 ℃, and keep the temperature for half an hour. Filter to get the filtrate. And concentrate it under reduced pressure until there is crystallization, stir to completely precipitate the crystallization, filter to take the crystallization, wash with 95% ethanol, and dry in vacuum below 60 ℃ to obtain L-cysteine hydrochloride without crystal water. Methods 2. enzymatic hydrolysis of DL-2-aminodihydrothiazolin-4-carboxylic acid (DL-ATC)
Last Update：2024-04-09 19:05:12
L-半胱氨酸,盐酸盐
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Product Name: L-Cysteine hydrochloride anhydrous Request for quotation
CAS: 52-89-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
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Guangzhou Yuanda New Material Co.,Ltd
Product Name: L-Cysteine hydrochloride anhydrous Request for quotation
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Email: 2470479589@qq.com
Mobile: +86 19849939632
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Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Acetylcysteine Impurity 2 Hydrochloride (Acetylcysteine EP Impurity B Hydrochloride) Visit Supplier Webpage Request for quotation
CAS: 52-89-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: L-Cysteine hydrochloride anhydrous Request for quotation
CAS: 52-89-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
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Spot supply
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CAS: 52-89-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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Hebei huafan biology science and technology co., ltd
Product Name: L-Cysteine Hydrochloride Anhydrous Request for quotation
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Tel:
Email:
Mobile: 15030876788
QQ: 370853650 Click to send a QQ messageSend QQ message
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L-半胱氨酸,盐酸盐
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