L-(-)-Threitol
L-Threitol
CAS: 2319-57-5
Molecular Formula: C4H10O4
L-(-)-Threitol - Names and Identifiers
| Name | L-Threitol |
| Synonyms | L-Threitol L-THREITOL L(-)-THREITOL L-(-)-Threitol L-1,2,3,4-BUTANETETROL L-1,2,3,4-Butanetetraol (2S,3S)-1,2,3,4-BUTANETETROL (2S,3S)-1,2,3,4-Butanetetrol (2S,3S)-Butane-1,2,3,4-tetraol (2S,3S)-(-)-1,2,3,4-BUTANETETROLE |
| CAS | 2319-57-5 |
| InChI | InChI=1S/C4H10O4/c5-1-3(7)4(8)2-6/h3-8H,1-2H2/t3-,4-/m0/s1 |
L-(-)-Threitol - Physico-chemical Properties
| Molecular Formula | C4H10O4 |
| Molar Mass | 122.12 |
| Density | 1.0151 (rough estimate) |
| Melting Point | 87-90°C(lit.) |
| Boling Point | 147.51°C (rough estimate) |
| Solubility | almost transparency in Methanol |
| Appearance | powder to crystal |
| Color | White to Almost white |
| BRN | 1719754 |
| pKa | 13.27±0.20(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.4502 (estimate) |
| MDL | MFCD00064294 |
L-(-)-Threitol - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3 |
L-(-)-Threitol - Introduction
L-Threitol(L-Threitol) is a chiral compound with the chemical name L-1,2,3, 4-tetrahydroxybutane. It is a six-carbon sugar alcohol molecule formed by four hydroxyl groups linked to a butane backbone.
L-Threitol is a colorless crystalline solid with high solubility in water. It has reversible high-temperature phase change properties, specifically, below 0 ° C is a tetrahydrate crystal phase, between 0 ° C and 15 ° C is an anhydrous crystal phase, and above 15 ° C is transformed into a tetrahydrate crystal phase. L-Threitol have asymmetric chiral structures that can be used as building blocks for chiral ligands or catalysts.
The main use of L-Threitol is as a reagent in organic synthesis and biochemistry. It can be used as a chiral auxiliary in the preparation of chiral drugs, hormone and peptide synthesis and other organic synthesis processes. In addition, L-Threitol can also be used as a carbon source in microbial culture media for microbial fermentation and biopharmaceuticals.
L-Threitol can be prepared by hydrogenation of caprolactone. Caprolactone is subjected to reduction reaction, and the catalyst is generally platinum or palladium, and the L-Threitol product can be obtained.
Regarding safety information, L-Threitol is a relatively safe compound under general conditions of use. However, as with all chemicals, it is important to follow laboratory procedures for safe handling. Direct contact between L-Threitol and skin should be avoided to prevent inhalation of dust or aerosols. At the same time, pay attention to the risk of fire and explosion when storing and handling this compound, and maintain good ventilation conditions. If necessary, personal protective equipment should be used and the relevant safety data sheet should be followed.
L-Threitol is a colorless crystalline solid with high solubility in water. It has reversible high-temperature phase change properties, specifically, below 0 ° C is a tetrahydrate crystal phase, between 0 ° C and 15 ° C is an anhydrous crystal phase, and above 15 ° C is transformed into a tetrahydrate crystal phase. L-Threitol have asymmetric chiral structures that can be used as building blocks for chiral ligands or catalysts.
The main use of L-Threitol is as a reagent in organic synthesis and biochemistry. It can be used as a chiral auxiliary in the preparation of chiral drugs, hormone and peptide synthesis and other organic synthesis processes. In addition, L-Threitol can also be used as a carbon source in microbial culture media for microbial fermentation and biopharmaceuticals.
L-Threitol can be prepared by hydrogenation of caprolactone. Caprolactone is subjected to reduction reaction, and the catalyst is generally platinum or palladium, and the L-Threitol product can be obtained.
Regarding safety information, L-Threitol is a relatively safe compound under general conditions of use. However, as with all chemicals, it is important to follow laboratory procedures for safe handling. Direct contact between L-Threitol and skin should be avoided to prevent inhalation of dust or aerosols. At the same time, pay attention to the risk of fire and explosion when storing and handling this compound, and maintain good ventilation conditions. If necessary, personal protective equipment should be used and the relevant safety data sheet should be followed.
Last Update：2024-04-09 21:11:58
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CAS: 2319-57-5
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CAS: 2319-57-5
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