L-5-HYDROXYTRYPTOPHAN
L-5-Hydroxytryptophan
CAS: 4350-09-8;314062-44-7
Molecular Formula: C11H12N2O3
L-5-HYDROXYTRYPTOPHAN - Names and Identifiers
| Name | L-5-Hydroxytryptophan |
| Synonyms | Oxyfan L-5HTP L-5-HTP Telesol Serotonyl pretonine Oxitriptan Oxitriptano Oxitriptanum 5-hydroxy-l-tryptopha L-5-HYDROXYTRYPTOPHAN L-5-Hydroxytryptophan 5-Hydroxy-L-tryptophan tryptophan, 5-hydroxy- 5-Hydroxyl-L-tryptophan L-tryptophan, 5-hydroxy- (-)-5-HYDROXY-L-TRYPTOPHAN Tryptophan, 5-hydroxy-, L- L-5-HYDROXYTRYPTOPHAN HYDRATE L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID 2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPIONIC ACID |
| CAS | 4350-09-8 314062-44-7 |
| EINECS | 224-411-1 |
| InChI | InChI=1/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16) |
L-5-HYDROXYTRYPTOPHAN - Physico-chemical Properties
| Molecular Formula | C11H12N2O3 |
| Molar Mass | 220.22 |
| Density | 0.902 g/mL at 25 °C (lit.) |
| Melting Point | 270 °C (dec.) (lit.) |
| Boling Point | 361.16°C (rough estimate) |
| Specific Rotation(α) | -32.5 º (c=1,H2O on dry basis) |
| Flash Point | 175°F |
| Water Solubility | Slightly soluble |
| Solubility | H2O: 10mg/mL |
| Appearance | White to white-like powder |
| Color | white |
| Merck | 14,4847 |
| BRN | 88200 |
| pKa | 2.22±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.4850(lit.) |
| MDL | MFCD00064341 |
| Physical and Chemical Properties | Melting Point: 270°C specific optical rotation -32.5 ° (c = 1,H2O on dry basis) water-soluble easily soluble |
L-5-HYDROXYTRYPTOPHAN - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R65 - Harmful: May cause lung damage if swallowed R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R20/21 - Harmful by inhalation and in contact with skin. |
| Safety Description | S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | YN7110000 |
| FLUKA BRAND F CODES | 3-10 |
| TSCA | Yes |
| HS Code | 29339990 |
| Hazard Class | 6.1 |
| Packing Group | III |
L-5-HYDROXYTRYPTOPHAN - Reference
| Reference Show more | 1. Chen Mingzhu, Chen Jing, Huang Youxia, Cheng Jing, Huang Gang. Ameliorative effect of total flavonoids of Prunus mume on depression in mice [J]. Modern medicine and clinic, 2017,32(02):170-174. 2. Wang Xichun, Zhu Xiaoyan, Zhang Yafei, etc. Effects of deoxynivalenol exposure on neurotransmitters, lipid peroxidation and calcium homeostasis in hippocampal neurons of piglets [J]. Chinese Journal of Animal Nutrition, 2018, 30(09):402-409. 3. Wei, Yingliang, Anting Wang, and Lu Wang.. INTERNATIONAL JOURNAL OF Pharmaceutical SCI |
L-5-HYDROXYTRYPTOPHAN - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| traits | 5-hydroxy-L-tryptophan is white to light yellow powder to crystalline. |
| use | 5-hydroxy-L-tryptophan is a precursor of serotonin. serotonin mainly affects mood and promotes happiness. it also affects appetite, sleep cycle and pain perception. It has the ability to suppress appetite, reduce fat intake, reduce anxiety, control emotions, promote sleep, and promote emotional and nervous system health. L-aromatic amino acid decarboxylase substrate. |
| biological activity | L-5-Hydroxytryptophan (L-5-HTP) is a natural amino acid and dietary supplement, which can be used as an antidepressant, appetite suppressant and sleep aid. It is the precursor of neurotransmitter serotonin and an antagonist of reserpine (reserpine). L-5-Hydroxytryptophan (L-5-HTP) can be used to study fibromyalgia, myoclonus, migraine and cerebellar ataxia. |
Last Update：2024-04-09 15:16:50
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