L-Arg(Pbf)-OH - Names and Identifiers
Name | (E)-N~5~-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-L-ornithine
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Synonyms | D-Arg(Pbf) L-Arg(Pbf) H-Arg(Pbf)-OH L-Arg(Pbf)-OH H-L-ARG(PBF)-OH · HCL Nω-(2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-L-ornithine (S)-2-amino-5-(3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonyl)guanidino)pentanoic acid (E)-N~5~-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-L-ornithine
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CAS | 200115-86-2
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InChI | InChI=1/C19H30N4O5S/c1-10-11(2)16(12(3)13-9-19(4,5)28-15(10)13)29(26,27)23-18(21)22-8-6-7-14(20)17(24)25/h14H,6-9,20H2,1-5H3,(H,24,25)(H3,21,22,23)/t14-/m0/s1 |
L-Arg(Pbf)-OH - Physico-chemical Properties
Molecular Formula | C19H30N4O5S
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Molar Mass | 426.53 |
Density | 1.39±0.1 g/cm3(Predicted) |
Boling Point | 613.2±65.0 °C(Predicted) |
Flash Point | 339°C |
Vapor Presure | 4.27E-17mmHg at 25°C |
pKa | 2.50±0.24(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Refractive Index | 1.617 |
L-Arg(Pbf)-OH - Introduction
(E)-N ~ 5 ~-(amino{[(2,2,4,6,7-pentamethyl-2,) sulfonyl]amino} methyllidene)-L-ornithine is an organic compound, the following describes its nature, use, preparation and safety information.
Nature:
(E)-N ~ 5 ~-(amino{[(2,2,4,6,7-pentamethyl-2,) sulfonyl]amino} methyllidene)-The L-ornithine is a colorless crystalline powder. It is stable at room temperature but reacts violently with oxygen. The solubility of the compound is poor, insoluble in water, soluble in acidic and alkaline solutions.
Use:
(E)-N ~ 5 ~-(amino{[(2,2,4,6,7-pentamethyl-2,) sulfonyl]amino} methyllidene)-L-ornithine is mainly used in biochemical research as a cofactor for enzymes.
Method:
Preparation of (E)-N ~ 5 ~-(amino{[(2,2,4,6,7-pentamethyl-2, phenyl) sulfonyl]amino} methyllidene)-L-ornithine methods are complex and usually require multiple reactions. One of the commonly used preparation methods includes the following steps:
1. The starting material is L-ornithine, ornithine methyl ester is prepared by esterification.
2. The ornithine methyl ester reacts with an appropriate amount of pentamethylfuryl sulfonyl chloride to generate the corresponding ornithine methyl ester sulfonyl chloride.
3. The reaction of ornithine methyl ester sulfonyl chloride with dihydroaminomethyl reagent yields (E)-N ~ 5 ~-(amino{[(2,2,4,6, 7-pentametyl-2,) sulfonyl]amino} methyllidene)-L-ornithine.
Safety Information:
(E)-N ~ 5 ~-(amino{[(2,2,4,6,7-pentamethyl-2,) sulfonyl]amino} methyllidene)-The L-ornithine has no special safety risks under normal use conditions. However, due to the lack of sufficient toxicological data, it is recommended to take standard laboratory safety practices during use, such as wearing appropriate protective gloves and eye protection equipment, and avoiding direct contact with skin and eyes. Avoid inhaling powder and operate in a well-ventilated area. Seek immediate medical help if touched or ingested by mistake.
Last Update:2024-04-09 15:17:54