Name | L(+)-Ornithine hydrochloride |
Synonyms | L-ORN HCL H-Orn-OH.HCl H-Orn-OH*HCl H-Orn-OH·HCl L-Ornithine HCl L-Ornithine.Hcl L-ORNITHINE HCL L-Ornithine, HCl L-ORNITHINE-OH HCL Ornithine hydrochloride L-Ornithine hydrochloride L-ORNITINE MONOCHLORHYDRATE L(+)-Ornithine hydrochloride L(+)-ORNITHINE HYDROCHLORIDE (2S)-2,5-diammoniopentanoate L(+)-Ornithine Hydrochloride L-ORNITHINE-OH HYDROCHLORIDE L-Ornithine Monohydrochloride L-ORNITHINE MONOHYDROCHLORIDE L-ORNITHINE HYDROCHLORIDE SALT L-(+)-ORNITHINE MONOHYDROCHLORIDE L-ornithine hcl cell culture tested (S)-(+)-2,5-Diaminopentanoic acid hydrochloride |
CAS | 3184-13-2 |
EINECS | 221-678-6 |
InChI | InChI=1/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+1/t4-/m0/s1 |
InChIKey | GGTYBZJRPHEQDG-WCCKRBBISA-N |
Molecular Formula | C5H13ClN2O2 |
Molar Mass | 168.62 |
Density | 1.57 |
Melting Point | 245°C (dec.)(lit.) |
Boling Point | 308.7°C at 760 mmHg |
Specific Rotation(α) | 24 º (c=4, 6N HCl) |
Flash Point | 140.5°C |
JECFA Number | 2120 |
Water Solubility | Soluble in water (543 mg/ml at 20°C), and alcohol. |
Solubility | Solubility in water: 543G/L (20 C), soluble in inorganic acid; Insoluble in most organic solvents |
Vapor Presure | 0.00015mmHg at 25°C |
Appearance | White crystal |
Color | White |
Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.06', , 'λ: 280 nm Amax: 0.06'] |
Merck | 14,6874 |
BRN | 3625847 |
PH | 5.0-6.0 (25℃, 1M in H2O) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Stability | Stable. |
Sensitive | Easily absorbing moisture |
Refractive Index | 24 ° (C=4, 6mol/L HC |
MDL | MFCD0006452 |
Physical and Chemical Properties | density 1.57 |
In vivo study | L-Ornithine and phenylacetate act synergistically in pigs with acute liver failure to slow the increase in arterial blood ammonia, significantly reduce extracellular brain ammonia, and prevent increased intracranial pressure. |
Hazard Symbols | Xi - Irritant |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
Safety Description | S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
RTECS | RM2985000 |
FLUKA BRAND F CODES | 3-10 |
TSCA | Yes |
HS Code | 29224995 |
Toxicity | LD50 orl-rat: 10 g/kg JPMSAE 62,49,73 |
Reference Show more | 1. Hu Cuicui, Li Qiuyan, Zhu Xiaojuan, etc. Isolation and identification of biogenic amine-producing bacteria from rice wine Koji [J]. Food Research and Development, 2017(19):170-174. 2. Ma linlong Liu Yanli Cao Dan Liu Panpan Wang Shengpeng Huang Yong Ming Jin Xiaofang. Analysis and evaluation model construction of different tea varieties (lines) of green tea taste [J]. Journal of Agricultural Engineering 2020 36(10):277-286. 3. [IF = 4.939] Lili Wen et al."Protein Aggregation and Performance Optimization Based on Microconformational Changes of Aromatic hydrophonic Regions." Mol Pharmaceut. 2018;15(6):2257-2267 4. [IF = 4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10 5. [IF=3.361] Ruixue Yu et al."Targeted neurotransmitter metabolomics profiling of oleanolic acid in the treatment of spontaneously hypertensive rats."Rsc Adv. 2019 Jul;9(40):23276-23288 |
amino acid drugs. Can activate the ornithine cycle, promote the liver ammonia toxicity. It is used together with L-arginine, L-citrulline and the like as an antidote and a liver function promoter.