L-a-tert-Butyl-Gly-OtBuHCl - Names and Identifiers
L-a-tert-Butyl-Gly-OtBuHCl - Physico-chemical Properties
Molecular Formula | C10H22ClNO2
|
Molar Mass | 223.74 |
Density | 0.930±0.06 g/cm3(Predicted) |
Boling Point | 87-89 °C(Press: 18 Torr) |
pKa | 7.97±0.37(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
L-a-tert-Butyl-Gly-OtBuHCl - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R22 - Harmful if swallowed
R51 - Toxic to aquatic organisms
|
L-a-tert-Butyl-Gly-OtBuHCl - Upstream Downstream Industry
L-a-tert-Butyl-Gly-OtBuHCl - Introduction
H-TBU-GLY-OTBU HCL(H-TBU-GLY-OTBU HCL) is an organic compound. Its properties are as follows:
1. Appearance: white crystalline powder
2. Molecular formula: C12H25NO2 · HCl
3. Molecular weight: 253.79g/mol
4. Melting Point: 162-165 ℃
5. Solubility: insoluble in water, soluble in organic solvents such as ethanol and dimethylformamide.
H-TBU-GLY-OTBU HCL is commonly used in synthesis and research, it has the following main uses:
1. As a reagent for protecting amino acids: it can be used to protect the hydroxyl group of α-amino acids, thereby avoiding or reducing the interference of other functional groups.
2. Synthetic peptides and proteins: can be used to synthesize specific amino acids in peptide chains or protein sequences.
3. Biomedical research: It is commonly used in the study of protein structure and function, and studies its role in proteins by changing or protecting specific amino acid residues.
The method for preparing H-TBU-GLY-OTBU HCL is as follows:
1. First, tert-butyl methylimidoyl chloride is reacted with glycine to obtain tert-butyl glycine.
2. Glycine tert-butyl ester is then reacted with sodium tert-butyl azide to form glycine tert-butyl ester with the temporary protecting group being tert-butoxycarbonyl.
3. Finally, tert-butanol and hydrochloric acid were added to the reaction system to obtain H-TBU-GLY-OTBU HCL.
For safety information, please observe the following precautions:
1. H-TBU-GLY-OTBU HCL should avoid direct contact with skin, eyes and mucous membranes to avoid irritation or injury.
2. In the operation, should wear appropriate personal protective equipment, such as gloves, goggles, etc.
3. When storing and handling the compound, keep the room in a dry and well ventilated environment.
4. H-TBU-GLY-OTBU HCL should be properly stored to avoid exposure to heat sources and open flames to avoid fire.
5. Please strictly abide by the rules and regulations for the storage and disposal of chemicals, and pay attention to prevent the leakage and discharge of chemicals to ensure the safety of individuals and the environment.
Last Update:2024-04-10 22:29:15