Name | SPK-601 |
Synonyms | SPK601 SPK-601 LMV-601 SPK 601 SPK-0601 Carbonodithioic acid rel-(-)-O-[(3aR,4R,5S,7R,7aR)-octahydro-4,7-methano-1H-inden-5-yl] ester potassium salt |
CAS | 1096687-52-3 |
Molecular Formula | C11H17KOS2 |
Molar Mass | 268.47 |
Storage Condition | -20℃ |
In vitro study | SPK-601 (72 hours; HPV-31 cells) displays a dose dependent inhibitory effect on cell growth ( IC 50 of 16 μg/mL), and inhibits HPV-31 specific RNA expression and DNA replication. Cell Viability Assay Cell Line: 9E human papilloma virus (HPV)-31 infected cervical epithelial cells Concentration: Incubation Time: 72 hours Result: A dose dependent inhibitory effect on cell growth. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.753 ml | 18.764 ml | 37.528 ml |
5 mM | 0.751 ml | 3.753 ml | 7.506 ml |
10 mM | 0.375 ml | 1.876 ml | 3.753 ml |
5 mM | 0.075 ml | 0.375 ml | 0.751 ml |
biological activity | SPK-601 (LMV-601) is a phosphatidylcholine specific phospholipase C (phosphatidylcholine-specific phospholipase C, PC-PLC) inhibitor, and can also be used as an antibacterial agent. |
target | PC-PLC |
in vitro study | SPK-601 (72 hours; HPV-31 cells) displays a dose dependent inhibitory effect on cell growth ( IC 50 of 16 μg/mL), and inhibits HPV-31 specific RNA expression and DNA replication. Cell Viability Assay Cell Line: 9E human papilloma virus (HPV)-31 infected cervical epithelial cells Concentration: incubation Time: 72 hours Result: A dose dependent inhibitory effect on cell growth. |
Cell Line: | 9E human papilloma virus (HPV)-31 infected cervical epithelial cells |
Concentration: | |
Incubation Time: | 72 hours |
Result: | A dose dependent inhibitory effect on cell growth. |