LXH254,LXH-254

Name	LXH254,LXH-254
Synonyms	LXH254 LXH-254 LXH 254 Naporafenib LXH254,LXH-254 4-Pyridinecarboxamide, N-[3-[2-(2-hydroxyethoxy)-6-(4-morpholinyl)-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)-
CAS	1800398-38-2

Molecular Formula	C25H25F3N4O4
Molar Mass	502.49
Density	1.353±0.06 g/cm3(Predicted)
Boling Point	601.9±55.0 °C(Predicted)
pKa	10.86±0.70(Predicted)
Storage Condition	Room Temprature
In vitro study	In a tumor model with BRAF V600 mutation, LXH254 not only inhibited MAPK signaling activity, but also inhibited mutant N-and KRAS-driven signaling. LXH254 can inhibit RAF monomer or dimer with equal efficacy. LXH254 has oral bioavailability and can cause tumor regression in a variety of cell lines and xenograft models derived from human primary tumors.

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Product Name: LXH254,LXH-254 Visit Supplier Webpage Request for quotation
CAS: 1800398-38-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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LXH254,LXH-254

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