Lateritine
Lateritin
CAS: 65454-13-9
Molecular Formula: C15H19NO3
Lateritine - Names and Identifiers
| Name | Lateritin |
| Synonyms | bassiatin Lateritin lateritin Lateritine (3S,6R)-Lateritin 4-Methyl-6-(1-methylethyl)-3-(phenylmethyl)-2,5-morpholinedione |
| CAS | 65454-13-9 |
Lateritine - Physico-chemical Properties
| Molecular Formula | C15H19NO3 |
| Molar Mass | 261.319 |
| Solubility | Soluble in DMSO |
| Storage Condition | -20℃ |
| Use | Lateritin is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor isolated from the mycelial cake of Gibberella lateritium; bassiatin is the (3S,6R) isomer. |
Lateritine - Reference
| Reference Show more | 1. Pettit RK, Pettit GR, Xu JP, Weber CA, Richert LA. Isolation of human cancer cell growth inhibitory, antimicrobial lateritin from a mixed fungal culture. Planta Med. 2010 Mar;76(5):500-1. doi: 10.1055/s-0029-1240617. Epub 2009 Nov 25. PubMed PMID: 19941263.2. Hasumi K, Shinohara C, Iwanaga T, Endo A. Lateritin, a new inhibitor of acyl-CoA:cholesterol acyltransferase produced by Gibberella lateritium IFO 7188. J Antibiot (Tokyo). 1993 Dec;46(12):1782-7. PubMed PMID: 8294234.3. Meng L, Tao H, Dong G, Yang T, Zhang W, Zhu W, Huang C. ERK1/2 and Akt pathway activated during (3R,6R)-bassiatin(1)-induced apoptosis in MCF-7 cells. Cell Biol Int. 2012 Apr 1;36(4):345-8. doi: 10.1042/CBI20110388. PubMed PMID: 22150072.4. Meng L, Feng B, Tao H, Yang T, Meng Y, Zhu W, Huang C. A novel antioestrogen agent (3R,6R)-bassiatin inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression in 17β-oestradiol-treated MCF-7 cells. Cell Biol Int. 2011 Jun;35(6):599-605. doi: 10.1042/CBI20100765. PubMed PMID: 21241249. |
Lateritine - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.827 ml | 19.134 ml | 38.269 ml |
| 5 mM | 0.765 ml | 3.827 ml | 7.654 ml |
| 10 mM | 0.383 ml | 1.913 ml | 3.827 ml |
| 5 mM | 0.077 ml | 0.383 ml | 0.765 ml |
Last Update：2024-01-02 23:10:35
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Product Name: Lateritin Visit Supplier Webpage Request for quotationCAS: 65454-13-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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