Linezolid-7
(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5- yl)methyl)formamide
CAS: 168828-65-7
Molecular Formula: C15 H18 F N3 O4
Linezolid-7 - Names and Identifiers
Linezolid-7 - Physico-chemical Properties
| Molecular Formula | C15 H18 F N3 O4 |
| Molar Mass | 323.32 |
| Density | 1.332±0.06 g/cm3(Predicted) |
| Boling Point | 580.6±50.0 °C(Predicted) |
| pKa | 15.40±0.23(Predicted) |
| In vivo study | Demethyl linezolid inhibits the activity of Staphylococcus aureus bacteria in mice with an ED 50 of 4.4 mg/kg by oral intubation. |
Linezolid-7 - Introduction
(S)-N-(3-(2-oxooxazolidin-5-yl)methyl)formamide is an organic compound with the chemical formula C16H18FN3O4.
It is a white to off-white solid, soluble in some organic solvents such as ethanol and dimethyl sulfoxide. It has a melting point of about 138-140°C.
(S)-N-((3-(over)-2-oxooxazolidin-5-yl)methyl)formamide has a wide range of applications. It is a very important synthetic intermediate that can be used to synthesize a variety of antibiotics and drugs. Because of its nitrogen-containing heterocyclic structure and fluorine atoms, it has a variety of biological activities in the field of medicine, such as antibacterial and antifungal activity.
The method of preparing (S)-N-((3-(o)-2-oxooxazolidin-5-yl)methyl)formamide can be used by adding an appropriate amount (S) reaction of-1-methoxyacetoxide chloride with 3-(3-fluoro-4-morpholinyl) benzoic acid to give (S)-3-(3-fluoro-4-morpholinyl)-2-oxo-l, 2,4-pyrazoline, followed by reaction with formamide to form (S)-N-((3-()-2-oxooxazolidin-5-yl)methyl)-formamide.
There is no specific report on the safety of this compound. However, based on the structure and properties of similar compounds, such compounds should be considered potentially hazardous. When using and handling the compound, it is recommended to take appropriate safety measures, such as wearing protective gloves, goggles and protective face shields, ensuring that the operation is carried out in a well-ventilated environment, and avoiding inhalation, ingestion and contact with skin. In the use and disposal process, please comply with the relevant laws and regulations and operating procedures. For detailed safety information, please refer to the product's safety data sheet (SDS).
It is a white to off-white solid, soluble in some organic solvents such as ethanol and dimethyl sulfoxide. It has a melting point of about 138-140°C.
(S)-N-((3-(over)-2-oxooxazolidin-5-yl)methyl)formamide has a wide range of applications. It is a very important synthetic intermediate that can be used to synthesize a variety of antibiotics and drugs. Because of its nitrogen-containing heterocyclic structure and fluorine atoms, it has a variety of biological activities in the field of medicine, such as antibacterial and antifungal activity.
The method of preparing (S)-N-((3-(o)-2-oxooxazolidin-5-yl)methyl)formamide can be used by adding an appropriate amount (S) reaction of-1-methoxyacetoxide chloride with 3-(3-fluoro-4-morpholinyl) benzoic acid to give (S)-3-(3-fluoro-4-morpholinyl)-2-oxo-l, 2,4-pyrazoline, followed by reaction with formamide to form (S)-N-((3-()-2-oxooxazolidin-5-yl)methyl)-formamide.
There is no specific report on the safety of this compound. However, based on the structure and properties of similar compounds, such compounds should be considered potentially hazardous. When using and handling the compound, it is recommended to take appropriate safety measures, such as wearing protective gloves, goggles and protective face shields, ensuring that the operation is carried out in a well-ventilated environment, and avoiding inhalation, ingestion and contact with skin. In the use and disposal process, please comply with the relevant laws and regulations and operating procedures. For detailed safety information, please refer to the product's safety data sheet (SDS).
Last Update：2024-04-09 21:54:55
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Spot supply
Product Name: Linezolid Impurity 86 Visit Supplier Webpage Request for quotationCAS: 168828-65-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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