Name | Liproxstatin-1 |
Synonyms | 152063 CS-1656 Liproxstatin-1 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine N-[(3-chlorophenyl)methyl]spiro[4H-quinoxaline-3,4'-piperidine]-2-amine N-[(3-chlorophenyl)methyl]-1'H-spiro[piperidine-4,2'-quinoxaline]-3'-amine N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine |
CAS | 950455-15-9 |
Molecular Formula | C19H21ClN4 |
Molar Mass | 340.8499 |
Solubility | DMSO: ≥ 31 mg/mL |
Appearance | powder |
Color | white to light brown |
Storage Condition | -20°C |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month. |
Physical and Chemical Properties | Bioactive Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM. |
Reference Show more | 1. [IF=5.048] Huawei Xia et al.Inhibiting ACSL1-Related Ferroptosis Restrains Murine Coronavirus Infection.Viruses-Basel. 2021 Dec;13(12):2383 2. [IF=6.313] Yijia Yang et al."Piperlongumine Inhibits Thioredoxin Reductase 1 by Targeting Selenocysteine Residues and Sensitizes Cancer Cells to Erastin."Antioxidants-Basel. 2022 Apr;11(4):710 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.934 ml | 14.669 ml | 29.338 ml |
5 mM | 0.587 ml | 2.934 ml | 5.868 ml |
10 mM | 0.293 ml | 1.467 ml | 2.934 ml |
5 mM | 0.059 ml | 0.293 ml | 0.587 ml |