Name | Lomerizine |
Synonyms | KB 2796 TERRANAS LOMERIZINE Lomerizine Lomerizine2HCl LOMERIZINE HCL LOMERIZINE DIHCL KB-2796 dihydrochloride Lomerizine hydrochloride Flometizine hydrochloride LOMERIZINE DIHYDROCHLORIDE N,N'-dibutylpropanediamide 1-[bis(4-fluorophenyl)methyl]-4-[2,3,4-trimethoxyphenylmethyl] 1-[bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine 1-(4,4'-Difluorobenzhydryl)-4-(2,3,4-trimethoxybenzyl)piperazine·dihydrochloride 1-[bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride 1-(Bis(4-fluorophenyl)methyl)-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride |
CAS | 101477-55-8 101477-54-7 |
InChI | InChI=1/C27H30F2N2O3.2ClH/c1-32-24-13-8-21(26(33-2)27(24)34-3)18-30-14-16-31(17-15-30)25(19-4-9-22(28)10-5-19)20-6-11-23(29)12-7-20;;/h4-13,25H,14-18H2,1-3H3;2*1H |
Molecular Formula | C27H32Cl2F2N2O3 |
Molar Mass | 541.46 |
Density | 1.203±0.06 g/cm3(Predicted) |
Melting Point | 214-218°C dec. |
Boling Point | 527.3±45.0 °C(Predicted) |
Flash Point | 272.7°C |
Solubility | DMSO: ≥30mg/mL |
Vapor Presure | 3.31E-11mmHg at 25°C |
Appearance | powder |
Color | white to tan |
Merck | 14,5563 |
pKa | 6.17±0.10(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
Physical and Chemical Properties | Appearance: white or white-like crystalline powder melting point: 206-209 ℃ X diffraction pattern: relevant substances in accordance with regulations: content in accordance with regulations: ≥ 99.0% manufacturer (current hit: 3/3 in total) [close window] jiankuquan warehouse Changzhou Xinhua industrial corporation jiankuquan warehouse Yixing zhongyu pharmaceutical technology co., ltd. jiankuquan warehouse Jintan Songsheng pharmaceutical and chemical research institute experimental factory |
Use | Used as a cerebrovascular dilator |
Risk Codes | R22 - Harmful if swallowed R50 - Very Toxic to aquatic organisms |
Safety Description | 61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3077 9 / PGIII |
WGK Germany | 3 |
RTECS | TK9189000 |
HS Code | 29335990 |
Toxicity | LD50 orally in mice: 300 mg/kg (Ohtaka) |