LoreclezoleHCl
Loreclezole
CAS: 117857-45-1
Molecular Formula: C10H6Cl3N3
LoreclezoleHCl - Names and Identifiers
LoreclezoleHCl - Physico-chemical Properties
| Molecular Formula | C10H6Cl3N3 |
| Molar Mass | 274.53 |
| Solubility | Soluble in DMSO |
| Storage Condition | Inert atmosphere,2-8°C |
| Use | Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors. |
| Target | GABAA |
LoreclezoleHCl - Reference
| Reference Show more | 1: Fisher JL, Hinkle DJ, Macdonald RL. Loreclezole inhibition of recombinant alpha1beta1gamma2L GABA(A) receptor single channel currents. Neuropharmacology. 2000 Jan 4;39(2):235-45. PubMed PMID: 10670419. 2: Borowicz KK, Sawiniec A, Czuczwar SJ. Interaction of loreclezole with conventional antiepileptic drugs in amygdala-kindled rats. Eur Neuropsychopharmacol. 2004 May;14(3):251-7. PubMed PMID: 15056485. 3: Borowicz KK, Czuczwar SJ. Effect of some convulsants on the protective activity of loreclezole and its combinations with valproate or clonazepam in amygdala-kindled rats. Pol J Pharmacol. 2003 Sep-Oct;55(5):727-33. PubMed PMID: 14704468. 4: Zhong Y, Simmonds MA. Interactions between loreclezole, chlormethiazole and pentobarbitone at GABA(A) receptors: functional and binding studies. Br J Pharmacol. 1997 Aug;121(7):1392-6. PubMed PMID: 9257919; PubMed Central PMCID: PMC1564829. |
LoreclezoleHCl - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.643 ml | 18.213 ml | 36.426 ml |
| 5 mM | 0.729 ml | 3.643 ml | 7.285 ml |
| 10 mM | 0.364 ml | 1.821 ml | 3.643 ml |
| 5 mM | 0.073 ml | 0.364 ml | 0.729 ml |
Last Update：2024-01-02 23:10:35
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