M-PEG-N3 - Names and Identifiers
M-PEG-N3 - Physico-chemical Properties
M-PEG-N3 - Introduction
M-PEG-N3(M-PEG-N3) is a chemical compound containing a methoxy group and a polyethylene glycol chain in its structure. It has some of the following properties:
1. Polyethylene glycol (PEG) chains impart water solubility to the compound, making it readily soluble in water and other polar solvents.
2. The interaction between the methoxy group and the molecule is weak, which makes the M-PEG-N3 have better solvent force and permeability.
3. The azide group (N3) is a highly reactive group that can be used for click chemistry (click chemistry) to react with other compounds containing alkyne or active double bond functional groups.
Purpose of M-PEG-N3:
1. In chemical biology research, it can be used as a labeling substance to realize the labeling and detection of biological molecules by clicking with bioactive molecules with alkyne groups.
2. In the study of drug delivery carriers, M-PEG-N3 can be used as a degradable crosslinking agent for the preparation of nanoparticles or colloids for drug delivery and release.
3. in materials science, M-PEG-N3 can be used for chemical modification to change the surface properties and compatibility of materials.
M-PEG-N3 preparation method:
A common preparation method is to prepare M-PEG-Cl by reacting methoxy-polyethylene glycol (M-PEG-OCH3) with trimethylsilyl chloride (TMSCl), and then reacting it with sodium azide (NaN3) to obtain M-PEG-N3.
M-PEG-N3 safety information:
1. M-PEG-N3 is a chemical and should be used under safe laboratory operation.
2. in case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help if necessary.
3. in the process of storage and handling, should avoid contact with oxidant or fire.
4. Wear appropriate personal protective equipment such as lab gloves, goggles, and lab coats.
5. Detailed safety operation guidelines and handling methods can be found in the relevant chemical safety data sheet (SDS), and read and follow before use.
Last Update:2024-04-09 18:58:34