M-TRIFLUOROMETHYLPROPIOPHENONE - Names and Identifiers
M-TRIFLUOROMETHYLPROPIOPHENONE - Physico-chemical Properties
Molecular Formula | C10H9F3O
|
Molar Mass | 202.17 |
Density | 1.202g/mLat 25°C(lit.) |
Melting Point | 18 °C |
Boling Point | 216-217°C(lit.) |
Flash Point | 227°F |
Vapor Presure | 0.405mmHg at 25°C |
Appearance | clear liquid |
Specific Gravity | 1.202 |
Color | Colorless to Light yellow |
BRN | 2101539 |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.4620(lit.) |
MDL | MFCD00000397 |
M-TRIFLUOROMETHYLPROPIOPHENONE - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
HS Code | 29147000 |
Hazard Class | IRRITANT |
M-TRIFLUOROMETHYLPROPIOPHENONE - Introduction
3-(trifluoromethyl)propiophenone is an organic compound with the chemical formula C9H7F3O. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 3-(trifluoromethyl)propiophenone is a colorless or pale yellow liquid.
-Melting point:-16 ℃
-Boiling point: 154-155 ℃
-Density: 1.343g/cm³
-Solubility: Soluble in organic solvents (such as alcohols, ethers and ketones), slightly soluble in water.
Use:
- 3-(trifluoromethyl)propiophenone is an important organic synthesis intermediate. It can be used to prepare drugs, dyes, pesticides and other chemicals.
-Due to its solubility in organic solvents, it is also commonly used as an additive in coatings, paints and glues.
Method:
The preparation method of 3-(trifluoromethyl)propiophenone is mainly obtained by reacting aromatic aldehyde with trifluoroethanone:
1. First, an aromatic aldehyde (such as benzaldehyde) is added to the reactor.
2. Add trifluoroethyl ketone while stirring and heating.
3. During the reaction, the gradual formation of the product was observed. After completion of the reaction, the pure 3-(trifluoromethyl)propiophenone can be extracted by distillation and purification steps.
Safety Information:
- 3-(trifluoromethyl)propiophenone is an organic compound and should be handled in accordance with the safe handling procedures for organic compounds.
-in the use of the process should avoid contact with skin and eyes, if accidental contact, should immediately rinse with plenty of water.
-Avoid inhaling its vapor, please use it in a well-ventilated place. If you encounter toxic combustion products, keep away from ignition sources and use respiratory protection.
-Please store 3-(trifluoromethyl)propiophenone properly, away from fire and high temperature environment, pay attention to moisture and prevent contact with other dangerous substances.
Last Update:2024-04-09 21:04:16