MC-VAL-CIT-PAB-PNB
L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-
CAS: 159857-81-5
Molecular Formula: C35H43N7O11
MC-VAL-CIT-PAB-PNB - Names and Identifiers
MC-VAL-CIT-PAB-PNB - Physico-chemical Properties
| Molecular Formula | C35H43N7O11 |
| Molar Mass | 737.76 |
| Density | 1.338±0.06 g/cm3(Predicted) |
| Boling Point | 1034.5±65.0 °C(Predicted) |
| Solubility | DMSO: ≥ 37 mg/mL |
| pKa | 13.24±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Physical and Chemical Properties | Bioactive MC-Val-Cit-PAB-PNP (Mc-Val-Cit-PABC-PNP) is an ADC peptide linker that can cleave cathepsin and can be used to synthesize antibody-coupled drugs (ADCs). |
| Use | Uses Maleimidoyl-L-valine-L-citrulline p-aminobenzyl alcohol p-nitrophenyl carbonate is an organic synthesis intermediate and a pharmaceutical intermediate, which can be used in the laboratory research and development process and the chemical and pharmaceutical synthesis process. |
MC-VAL-CIT-PAB-PNB - Upstream Downstream Industry
MC-VAL-CIT-PAB-PNB - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.355 ml | 6.777 ml | 13.555 ml |
| 5 mM | 0.271 ml | 1.355 ml | 2.711 ml |
| 10 mM | 0.136 ml | 0.678 ml | 1.355 ml |
| 5 mM | 0.027 ml | 0.136 ml | 0.271 ml |
Last Update：2024-01-02 23:10:35
MC-VAL-CIT-PAB-PNB - Target
Cleavable
Last Update：2024-04-10 22:29:15
MC-VAL-CIT-PAB-PNB - Reference Information
| use | maleimidoyl-L-valine-L-citrulline p-aminobenzyl alcohol p-nitrophenyl carbonate is an organic synthesis intermediate and a pharmaceutical intermediate, which can be used in the laboratory research and development process and the chemical and pharmaceutical synthesis process. |
| biological activity | MC-Val-Cit-PAB-PNP (Mc-Val-Cit-PABC-PNP) is an ADC peptide linker that can cleave cathepsin and can be used to synthesize antibody-coupled drugs (ADCs). |
| target | Cleavable |
Last Update：2024-04-09 21:54:55
Supplier List
Spot supply
Product Name: Mc-Val-Cit-PABC-PNP Visit Supplier Webpage Request for quotationCAS: 159857-81-5
Tel: 18301782025
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Mobile: 18021002903
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Spot supply
Product Name: Mc-Val-Cit-PABC-PNP Visit Supplier Webpage Request for quotationCAS: 159857-81-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for MC-VAL-CIT-PAB-PNB
BIS(4-NITROPHENYL) CARBONATE
N-Succinimidyl 6-maleimidohexanoate
MC-Val-Cit-PAB
Val-cit-PAB-OH
H-Cit-PABA
Fmoc-Cit-PABA
6-Maleimidocaproic acid
4-Nitrophenyl chloroformate
FMOC-VAL-OSU
FMoc-Val-Cit-PAB
6-Aminocaproic acid
N-Succinimidyl 6-maleimidohexanoate
MC-Val-Cit-PAB
Val-cit-PAB-OH
H-Cit-PABA
Fmoc-Cit-PABA
6-Maleimidocaproic acid
4-Nitrophenyl chloroformate
FMOC-VAL-OSU
FMoc-Val-Cit-PAB
6-Aminocaproic acid